Current Methods of Measuring Intracranial Pressure are Invasive, Expensive, and Risky. The current method for measuring intracranial pressure involves drilling a hole in the skull and physically inserting a sensor into the brain.Because this procedure is invasive and introduces additional risk factors, it is only used for patients in critical condition, typically in a coma. In 98% of traumatic brain injuries, the intracranial pressure is never tested. This leaves patients vulnerable to brain damage, seizure, coma, stroke, or even death.CranioSense has developed IPASS, a technology that measures intracranial pressure in seconds, without the need to drill a hole in the skull or insert a sensor into the brain. IPASS measures intracranial pressure (ICP) with an easy-to-use system that only requires a patch on the forehead, two clip-on sensors, and a handheld device the size of an iPad.In this episode, we discuss how Ryan Myers of CranioSense is discovering what their beachhead market should be, how to build the right team, and navigate between grant and venture funding to co-develop a winning medical product.

Wound care is one of the biggest healthcare burdens costing as much as $100 Billion every year in the US alone, with infection being a major contributing factor. So imagine you could have an intelligent band aid that automatically spotlights early detection of infections! Tune in to learn more about the scale of this ever-growing problem and how Chelsea has built ParaNano’s team from ideation to an investment backed venture. As a non-technical founding team, this discussion provides a stack of insight into how to bootstrap, navigate a complex product development pathway, and stay balanced along the journey.

Want to know what an alpaca has to do with manufacturing innovation, or what it takes to build out a great supply chain with the right partners?Sounds like something worth hearing more about! In this episode you can learn how the team from FORGE helps founders, and companies of all sizes, build out their supply chain to connect with the right manufacturing partner, at the right time.For any startup, it can be daunting knowing which manufacturing process or supplier to adopt, FORGE helps break down these barriers. Tune in to discover how this not-for-profit organization bridges the knowledge, experience, and key connections needed to enable taking innovation from prototype to IMPACT!Not only that, they follow the mantra, if it can be designed locally, it can be built locally, helping to better connect the innovation ecosystem. This is a pivotal group that every startup making a product needs to know about!

From the Silicon Valley of the East, via the startup nation, Sreekar Kothamachu had a fantastic vantage point to learn how medtech entrepreneurs were implementing leapfrog innovation to bring game changing solutions to patients. Building on this knowledge, Nesa Medtech has been developed through a deep understanding of the personal journey patients experience when suffering from Uterine Fibroids, non-cancerous tumors in the uterus. Millions of women have debilitating symptoms from these fibroids, often in silence. Learn how Sreekar is leading Nesa on a mission to create a revolutionary scarless treatment that can leapfrog the status quo! Tune in and share this story to help put an end to those suffering in silence.

It takes a true visionary to disrupt the medtech space! Step forward Diana Hall, CEO and Founder of ActivArmor. Diana's story is a heartfelt mission to transform how we provide orthopedic casts for patients around the world. ActivArmor's solution is based on the best components of lean manufacturing and distributed supply chains. A custom approach for producing casts that are hygenic, breathable, improve healing, and offer enhanced lifestyle freedom. Tune in to learn about Diana's journey from idea to a revenue generating product.

There have been fantastic advancements in robotic surgery but challenges remain around the level of haptic feedback and visual information for surgeons. Endoglow has developed a novel solution to illuminate this visualization problem, helping to improve real time decision-making during surgery. In this episode, you can learn about Dr. Doyle’s inspiration, her team's incredible progress developing a technical medical device, and how Endoglow is truly exposing the surgical planes through their Tissue Reveal Technology (TRT).

Today we're shining a light on Wendy Slone and her novel inside out approach to woundcare. It's clear starting a medical device is tough as you navigate complex regulatory, reimbursement, and scientific hurdles, all while trying to convince investors to fund your journey! Wendy's inspirational personal story behind her technology and energizing approach to developing a truly innovative product provide some great lessons for entrepreneurs.

Mitral regurgitation is the most frequent valve disease in the world affecting more than 2% of the general population. The current standard of care is open heart surgical repair of the valves but is there another option? CEO and Founder Toufic Azar of Meacor is developing an innovative minimally invasive approach that could transform treatment. Tune in to learn more about how Toufic got started, and how he is navigating taking a novel medical device to market!

A founder’s journey into entrepreneurship often has a compelling backstory behind it, and this week we’re fortunate to be able to share that of Geetha Manjunath, CEO of Niramai. Geetha provides an intimate insight into her career path and inspiration behind creating a low-cost, radiation-free tool for early detection of breast cancer. Under her leadership, Niramai is demonstrating the best aspects of utilizing Artificial Intelligence (AI) to make an impact in healthcare and save lives. Tune in to learn more about one of India’s leading innovators! 

Casey Grage, CEO and Co-founder of Hubly Surgical, joins the podcast sharing insights into her personal journey as a medtech entrepreneur, and what it takes to go from business idea to FDA approval. Lots to take away from Casey who is a fantastic leader, and sets a great example of how to stay milestone focused while communicating with your key stakeholders along the way!