This episode is brought to you by Rupa Health, AG1, Beekeepers, and Super Simple Grassfed Protein.  Blood pressure is one of the key markers of metabolic health, yet high blood pressure is very common—and the numbers are growing. Moreover, 93 percent of Americans are metabolically unhealthy. In fact, high blood pressure is often called a silent killer as it can lead to conditions such as heart disease, kidney failure, and stroke, and many people don’t even know they have it. In today’s episode, I talk with Dr. George Papanicolaou and Dr. Cindy Geyer about the seriousness of high blood pressure, the misconceptions around salt intake and blood pressure, what foods and supplements support healthy blood pressure, and overall metabolic health. Dr. George Papanicolaou is a graduate of the Philadelphia College of Osteopathic Medicine and is board certified in family medicine from Abington Memorial Hospital. He is also an Institute for Functional Medicine practitioner. Upon graduation from his residency, he joined the Indian Health Service. He worked on the Navajo reservation for four years at the Chinle Comprehensive Medical Facility, where he served as the Outpatient Department Coordinator. In 2000, he founded Cornerstone Family Practice in Rowley, MA. He began training in Functional Medicine through the Institute for Functional Medicine. In 2015, he established Cornerstone Personal Health, a practice dedicated entirely to Functional Medicine. Dr. Papanicolaou joined The UltraWellness Center in 2017. Dr. Cindy Geyer received her bachelor of science and her doctor of medicine degrees, with honors, from the Ohio State University. She completed her residency in internal medicine at Strong Memorial Hospital in Rochester, NY, and is triple board certified in internal medicine, integrative medicine, and lifestyle medicine. She joined The Ultrawellness Center in 2021 after practicing and serving as the medical director at Canyon Ranch for 23 years. This episode is brought to you by Rupa Health, AG1, Beekeepers, and Super Simple Grassfed Protein.  Access more than 3,000 specialty lab tests with Rupa Health. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com today. Head to drinkAG1.com/HYMAN to receive 10 FREE travel packs of AG1 with your first purchase. Go to beekeepersnaturals.com/HYMAN and enter code HYMAN to get Beekeeper’s Naturals' exclusive offer of 20% off sitewide. Right now, you can get 10% off Super Simple Grassfed Protein by heading to drhyman.com/protein and using code protein10. Full-length episodes (and corresponding links) of these interviews can be found here: Dr. George Papanicolaou Dr. Cindy Geyer Dr. Mark Hyman Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Rupa Health, Joovv, and Super Simple Grassfed Protein. The food industry wants us to believe that cooking is difficult, time-consuming, inconvenient, and expensive. And knowing we all have busy lives, fast food manufacturers and grocers lure us into convenient, heavily processed meals that take a toll on our waistline, our overall health, and, believe it or not, our budget. Today, over 50 percent of meals are consumed outside the home. We’ve raised several generations of Americans who don’t know how to cook. And it’s killing us. In today’s episode of my series I’m calling Health Bites, I discuss how to reconnect with your kitchen and just how inexpensive eating healthy and preparing your own food can be.  This episode is brought to you by Rupa Health, Joovv, and Super Simple Grassfed Protein. Access more than 3,000 specialty lab tests with Rupa Health. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com today. For a limited time, get an exclusive discount on Joovv’s Generation 3.0 devices (some exclusions apply). Go to Joovv.com/farmacy and use the code FARMACY. Right now, you can get 10% off Super Simple Grassfed Protein by heading to drhyman.com/protein and using code protein10. Here are more details from our interview (audio version / Apple Subscriber version): Challenges to eating healthy (2:58 / 1:28) The expensive cost of cheap food (9:26 / 7:18) Eating healthy for less (12:35 / 9:50) Dispelling common “healthy eating on a budget” myths (14:58 / 12:10) Strategies for eating well on a budget (17:08 / 14:58)  Mentioned in this episode Environmental Working Group (EWG)’s Good Food on a Tight Budget EWG’s Dirty Dozen List Thrive Market Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Rupa Health, Sensate, ButcherBox, and Thrive Market. We’re in the midst of a psychedelic renaissance. Compounds that have long been considered recreational drugs by conventional standards are finally being recognized through science as powerful tools for overcoming hard-to-treat health issues like PTSD, depression, addiction, and more.  Today on The Doctor’s Farmacy, I’m excited to talk to my good friend and one of the world’s most renowned mycologists, Paul Stamets, all about psilocybin and how this compound is helping us reimagine our way of treating one of the most important public health crises today—mental illness.  Paul Stamets is a speaker, author, mycologist, medical researcher, and entrepreneur and is considered an intellectual and industry leader in fungi: habitat, medicinal use, and production. His breakthrough research has created a paradigm shift for helping ecosystems worldwide. He has received numerous awards, including Invention Ambassador for the American Association for the Advancement of Science (AAAS), the National Mycologist Award from the North American Mycological Association (NAMA), and the Gordon & Tina Wasson Award from the Mycological Society of America (MSA). In 2020, Paul was inducted into the Explorer’s Club. He has been awarded myriad patents in the field of mycology. Paul is the founder and sole owner of Fungi Perfecti, LLC, the maker, and marketer of the category-leading myco-supplement Host Defense line. This episode is brought to you by Rupa Health, Sensate, ButcherBox, and Thrive Market. Access more than 3,000 specialty lab tests with Rupa Health. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com today. Head on over to getsensate.com/Farmacy and use code FARMACY to get 10% off your Sensate device today. For new members of ButcherBox, you can receive New York strip steaks for a year PLUS $20 off your first order. Go to ButcherBox.com/farmacy and use code FARMACY. Thrive Market is offering 30% off your first order and a free gift of up to $60 if you sign up now! Head over to thrivemarket.com/Hyman today. Here are more details from our interview (audio version / Apple Subscriber version): Why we should care about mushrooms (6:50 / 4:39) Why mushrooms are the zeitgeist of our time (12:35 / 10:00)  Health benefits of mushrooms (13:54 / 12:07)  How psilocybin works in human brains (29:34 / 25:48)  Psilocybin as treatment for mental health and addiction (33:07 / 28:55)  Specific psilocybin molecules that influence us neurologically (40:04 / 35:46) Research on psilocybin for mental health issues (51:58 / 48:06) The Stamets Stack microdosing method (1:02:41 / 58:57) The future of psilocybin use in our society (1:15:43 / 1:11:50)  A day in the life of Paul Stamets (1:20:16 / 1:16:22)  Learn more at paulstamets.com. Learn more about your ad choices. Visit megaphone.fm/adchoices

Hey podcast community, Dr. Mark here. My team and I are so excited to offer you a 7 Day Free trial of the Dr. Hyman+ subscription for Apple Podcast. For 7 days, you get access to all this and more entirely for free!  It's so easy to sign up. Just go click the Try Free button on the Doctor’s Farmacy Podcast page in Apple Podcast.  In this teaser episode, you’ll hear a preview of our latest Dr. Hyman+ Functional Medicine Deep Dive on food and mood with Dr. Deanna Minich. To learn more about the Institute of Functional Medicine, sign up for IFM’s newsletter: https://www.ifm.org/about/free-newsletter/. Want to hear the full episode? Subscribe now. With your 7 day free trial to Apple Podcast, you’ll gain access to audio versions of: - Ad-Free Doctor’s Farmacy Podcast episodes - Exclusive monthly Functional Medicine Deep Dives - Monthly Ask Mark Anything Episodes  - Bonus audio content exclusive to Dr. Hyman+ Trying to decide if the Dr. Hyman+ subscription for Apple Podcast is right for you?  Email my team at [email protected] with any questions you have.   Please note, Dr. Hyman+ subscription for Apple Podcast only includes Dr. Hyman+ in audio content. Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Mitopure, AG1, Zero Acre, and Super Simple Protein.  In small doses, stress can be beneficial. However, experiencing too much stress for too long, creates an intense demand for hormones like cortisol and adrenaline to be released. This can lead to adrenal fatigue, or adrenal dysfunction, which could result in burnout, fatigue, weight gain, and so much more. In today’s episode, I talk with Drs. Elizabeth Boham, Izabella Wentz, and Rangan Chatterjee about the link between chronic stress, cortisol, and adrenal dysfunction and how to choose joy to reduce stress. Dr. Elizabeth Boham is a physician and nutritionist who practices Functional Medicine at The UltraWellness Center in Lenox, MA. Through her practice and lecturing she has helped thousands of people achieve their goals of optimum health and wellness. She witnesses the power of nutrition every day in her practice and is committed to training other physicians to utilize nutrition in healing. Dr. Izabella Wentz is an internationally acclaimed thyroid specialist and a licensed pharmacist who has dedicated her career to addressing the root causes of autoimmune thyroid disease after being diagnosed with Hashimoto’s thyroiditis in 2009. She is the author of three books on Hashimoto’s: Hashimoto’s Thyroiditis Lifestyle Interventions for Finding and Treating the Root Cause, Hashimoto’s Food Pharmacology, and Hashimoto’s Protocol. Her latest book is Adrenal Transformation Protocol: A 4-Week Plan to Release Stress Symptoms and Go from Surviving to Thriving. Dr. Rangan Chatterjee is regarded as one of the most influential doctors in the UK and wants to change how medicine will be practiced for years to come. He hosts the biggest health podcast in Europe, Feel Better, Live More, which Apple has announced as one of the most downloaded new podcasts of the past year. His first book, How to Make Disease Disappear, is an international bestseller all over the world and has sold over 250,000 copies worldwide. This episode is brought to you by Mitopure, AG1, Zero Acre, and Super Simple Protein.  Support the growth of new healthy mitochondria and get 10% off of Mitopure. Head to timelinenutrition.com/drhyman and use code DRHYMAN10 at checkout. Head to drinkAG1.com/HYMAN to receive 10 FREE travel packs of AG1 with your first purchase. Zero Acre Oil is an all-purpose cooking oil. Go to zeroacre.com/MARK or use code MARK to redeem an exclusive offer. You can get 10% off Super Simple Grass Fed Protein by heading to drhyman.com/protein and use code protein10. Full-length episodes (and corresponding links) of these interviews can be found here: Dr. Elizabeth Boham Dr. Izabella Wentz Dr. Rangan Chatterjee Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Rupa University, AG1, and Super Simple Grassfed Protein. When it comes to overall health and weight loss, there’s an excess of advice out there. Unfortunately, most of it is misguided, outdated, and scientifically disproven. I’ve dedicated my career to finding and telling the truth about what makes us sick and fat and, most importantly, to the study of food as medicine and the science of creating health. In today’s episode of my series I’m calling Health Bites, I talk about four prevalent food myths that can create weight-loss roadblocks and even damage your health.  This episode is brought to you by Rupa Health, AG1, and Super Simple Grassfed Protein. If you’re a healthcare provider who wants to learn more about Functional Medicine testing, go to rupauniversity.com to sign up for a free live class or a boot camp! Head to drinkAG1.com/HYMAN to receive 10 FREE travel packs of AG1 with your first purchase. Right now, you can get 10% off Super Simple Grassfed Protein by heading to drhyman.com/protein and using code protein10. Here are more details from our interview (audio version / Apple Subscriber version): Myth #1: All calories are created equally (3:51 / 2:15) Myth #2: Your genetics define you and your health (12:50 / 10:34) Myth #3: You can out-exercise a bad diet (15:51 / 13:36) Myth #4: Eating fat makes you fat (17:48 / 15:31)  Mentioned in this episode The Carbohydrate-Insulin Model of Obesity: Beyond ‘Calories In, Calories Out’ Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Rupa Health, Super Simple Grassfed Protein, Sensate, and AquaTru. Our diets are the main driver of the chronic disease epidemic we are experiencing today. But food is also the most powerful medicine available to heal chronic diseases. The food we eat literally serves as information, instructions, or code that controls almost every function of the body—including our hormones, appetite, brain chemistry, immune system, gene expression, and even the microbiome.  Today on The Doctor’s Farmacy, I’m excited to talk to Mark Walker about incorporating food as medicine into the healthcare system, how we can prescribe food as physicians, and what it will mean for our nation's health and economy. Mark Walker is the Chairman and CEO of Performance Kitchen, the leading Food Is Medicine® company revolutionizing the US Healthcare System. Performance Kitchen specializes in the use of Medically Tailored Meals to treat chronic diseases. Mark is one of the leading experts in the country on the new industry of Food Is Medicine, which is the application of healthy food paid for by the US Healthcare System. Mark is a CPA and the founder of Dugout Ventures, an athlete-based investment group with Hall of Fame baseball player partners like David Ortiz, Nolan Ryan, and Barry Larkin. This episode is brought to you by Rupa Health, Super Simple Grassfed Protein, Sensate, and AquaTru.    Access more than 3,000 specialty lab tests with Rupa Health. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com today. You can get 10% off Super Simple Grassfed Protein by heading to drhyman.com/protein and use code protein10. Head on over to getsensate.com/Farmacy and use code FARMACY to get 10% off your Sensate device today. Go to drhyman.com/filter to get $100 OFF the AquaTru water filter. Here are more details from our interview (audio version / Apple Subscriber version): The current state of our “healthcare” system (4:50 / 3:17)  The effectiveness of food as medicine (7:47 / 6:30) Incorporating food as medicine into our existing healthcare system (9:21 / 7:48) How payers benefit from food as medicine (13:16 / 12:00)  Medically tailored meals (14:59 / 13:42) The economics of food as medicine (21:47 / 18:41)  Obstacles around prescribing food as medicine (31:59 / 26:50) Accessing medically tailored meal benefits (39:01 / 33:40) How Performance Kitchen is interfacing in this space (42:40 / 39:05) Mark’s personal story reversing prediabetes (47:08 / 43:33)  Learn more at performancekitchen.com. Find the Meal Benefit Locator tool here and download the Performance Kitchen Whitepaper here. Learn more about your ad choices. Visit megaphone.fm/adchoices

Hey podcast community, Dr. Mark here. My team and I are so excited to offer you a 7 Day Free trial of the Dr. Hyman+ subscription for Apple Podcast. For 7 days, you get access to all this and more entirely for free!  It's so easy to sign up. Just go click the Try Free button on the Doctor’s Farmacy Podcast page in Apple Podcast.  In this teaser episode, you’ll hear a preview of our monthly Ask Mark Anything episode. Want to hear the full episode? Subscribe now. With your 7 day free trial to Apple Podcast, you’ll gain access to audio versions of: - Ad-Free Doctor’s Farmacy Podcast episodes - Exclusive monthly Functional Medicine Deep Dives - Monthly Ask Mark Anything Episodes  - Bonus audio content exclusive to Dr. Hyman+ Trying to decide if the Dr. Hyman+ subscription for Apple Podcast is right for you?  Email my team at [email protected] with any questions you have.   Please note, Dr. Hyman+ subscription for Apple Podcast does not include access to the Dr. Hyman+ site and only includes Dr. Hyman+ in audio content.  Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Rupa Health, Joovv, Pendulum, and Super Simple Protein.  Mitochondria are the energy powerhouses of each cell in the body. Unfortunately, our modern diet and lifestyle compromise our mitochondria, which results in suboptimal function of the brain and other organs, reduced energy levels, and even cancer. Luckily, there are science-based practices like cold water therapy that we can do to improve the mitochondrial function of our cells, reduce inflammation, support the immune system, boost metabolism, and more. In today’s episode, I talk with Drs. Chris Rinsch and Stuart Phillips, Wim Hof, Dr. Susanna Søberg, and Dr. Steven Gundry about how to improve the mitochondrial function of our cells, reduce inflammation, and more. Dr. Chris Rinsch is the cofounder and CEO of Amazentis, an innovative life science company dedicated to employing breakthrough research and clinical science to bring advanced therapeutic nutrition products to life. Dr. Stuart Phillips is a professor in the Department of Kinesiology and a member of the School of Medicine at McMaster University. Wim Hof, also known as “The Iceman,” holds multiple world records for his feats of endurance and exposure to cold, and he is the author of The Wim Hof Method: Activate Your Full Human Potential. Dr. Susanna Søberg has a PhD in metabolism and specializes in functional breathing and cold and heat exposure for health optimization. She is the founder and CEO of the Soeberg Institute, where she teaches people how to “stress up to stress down” using natural stressors. Dr. Steven Gundry is one of the world’s top cardiothoracic surgeons and a pioneer in nutrition as well as a medical director at the International Heart and Lung Institute Center for Restorative Medicine. This episode is brought to you by Rupa Health, Joovv, Pendulum, and Super Simple Protein.  Access more than 3,000 specialty lab tests with Rupa Health. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com today. For a limited time, get an exclusive discount on Joovv’s Generation 3.0 devices (some exclusions apply). Go to Joovv.com/farmacy and use the code FARMACY. Pendulum is offering my listeners 20% off their first month of an Akkermansia subscription with code HYMAN. Just head over to Pendulumlife.com to check it out. You can get 10% off Super Simple Grassfed Protein by heading to drhyman.com/protein and using code protein10. Full-length episodes (and corresponding links) of these interviews can be found here: Drs. Chris Rinsch and Stuart Phillips Wim Hof Dr. Susanna Søberg Dr. Steven Gundry Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Rupa Health, AG1, and Super Simple Grassfed Protein. It’s time to think about immunity in a new way. There’s been a lot of focus recently on “boosting” your immune system. However, boosting immunity merely exaggerates all the defects of an aging immune system, whereas rejuvenation reboots immunity from your cells up. Rejuvenation is way more foundational and longer lasting than a basic boost because it uses your built-in programming to rebalance and optimize that system’s function.  In today’s episode of my series I’m calling Health Bites, I dive into immuno-rejuvenation—what it is, how it happens in the body, and my top strategies for switching it on.  This episode is brought to you by Rupa Health and Super Simple Grassfed Protein. Access more than 3,000 specialty lab tests with Rupa Health. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com today. Head to drinkAG1.com/HYMAN to receive 10 FREE travel packs of AG1 with your first purchase. Right now, you can get 10% off Super Simple Grassfed Protein by heading to drhyman.com/protein and using code protein10. Here are more details from our interview (audio version / Apple Subscriber version): Why rejuvenation is better than the conventional approach to immune health (5:37 / 3:55) How rejuvenation happens in the body (7:06 / 4:22) Activating our body’s own immuno-rejuvenation (11:05 / 8:25) How positive stress is rejuvenating (13:38 / 11:22)  Examples of positive stressors (16:52 / 14:37)  Mentioned in this episode Big Bold Health Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Rupa Health, BiOptimizers, LMNT, and Cozy Earth. Heart disease is still the number one killer in the world, yet most people don’t actually understand what markers put them most at risk.  The general consensus is there are two types of cholesterol—the good and the bad—the good is thought to be high-density lipoproteins or HDL, and the bad is low-density lipoproteins or LDL. But we now know from research that it's much more complicated than that—there are actually various sizes and densities of these lipoproteins.  Today on The Doctor’s Farmacy, I’m excited to talk to one of the leading lipidologists, Dr. Ronald Krauss, all about lipoproteins, what they do in the body, what they mean for heart disease risk, and why a typical lipid panel alone is insufficient. Dr. Krauss is a Senior Scientist at Children’s Hospital Oakland Research Institute, a Professor of Medicine at UCSF, and an Adjunct Professor of Nutritional Sciences at UC Berkeley. Dr. Krauss’s research aims to understand how to best prevent cardiovascular disease through early detection and management of its major risk factors: most notably, elevated levels of blood cholesterol and lipoproteins. He has published over 450 research articles and reviews on metabolic, genetic, dietary, and drug effects on plasma lipoproteins and the risk of coronary artery disease, with over 100,000 citations of this work. This episode is brought to you by Rupa Health, BiOptimizers, LMNT, and Cozy Earth. Access more than 3,000 specialty lab tests with Rupa Health. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com today. This month only you can get a FREE bottle of BiOptimizers Magnesium Breakthrough. Just go to magbreakthrough.com/hymanfree and enter coupon code hyman10. Right now, LMNT is offering my listeners a free sample pack with any purchase. Head over to DrinkLMNT.com/hyman today. Right now, get 40% off your Cozy Earth sheets. Just head over to cozyearth.com and use code DRHYMAN. Here are more details from our interview (audio version / Apple Subscriber version): How Dr. Krauss came to understand how cholesterol actually impacts the risk of heart disease (5:00 / 2:44) What is cholesterol? (9:00 / 6:37)  Statins as heart disease treatment (13:36 / 11:29)  Combatting myths around saturated fat (14:42 / 12:37)  The assay Dr. Krauss developed to differentiate between the different sizes of lipoproteins and what they mean for heart disease risk (29:58 / 25:40) Testing beyond the standard lipid panel (39:51 / 35:31) Insulin resistance, prediabetes, and heart disease (46:35 / 41:50)  Personal variation in heart disease risk (52:52 / 48:34)  Dietary approaches to preventing heart disease (1:01:07 / 56:56)  Research mentioned in this episode Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Rupa University, Mitopure, Levels, and Super Simple Protein.  Fatty liver is a dangerous yet misunderstood disease that is growing more and more common, and its effects are numerous. Fatty liver happens when fat replaces your liver cells and thereby compromises its important functions, thus increasing inflammation in the body. Surprisingly, it is not fat that causes a fatty liver, but sugar and starch. In today’s episode, I talk with Dr. Elizabeth Boham, Dr. Robert Lustig, and Shawn Stevenson about the importance of our liver and how to support it. Dr. Elizabeth Boham is a physician and nutritionist who practices Functional Medicine at The UltraWellness Center in Lenox, MA. Through her practice and lecturing she has helped thousands of people achieve their goals of optimum health and wellness. She witnesses the power of nutrition every day in her practice and is committed to training other physicians to utilize nutrition in healing. Dr. Robert Lustig is a neuroendocrinologist with expertise in metabolism, obesity, and nutrition. He’s the Emeritus Professor of Pediatrics in the Division of Endocrinology and a member of the Institute for Health Policy Studies at UCSF. He is also one of the leaders of the current “anti-sugar” movement that is changing the food industry, in part through his game-changing books. Shawn Stevenson is the author of the international bestselling book Sleep Smarter and creator of The Model Health Show, featured as the number one health podcast in the US, with millions of listener downloads each year. A graduate of the University of Missouri–St. Louis, Shawn studied business, biology, and nutritional science and went on to found Advanced Integrative Health Alliance, a company that provides wellness services for individuals and organizations worldwide. This episode is brought to you by Rupa University, Mitopure, Levels, and Super Simple Protein.  If you’re a healthcare provider who wants to learn more about Functional Medicine testing, go to rupauniversity.com to sign up for a free live class or a boot camp! Support the growth of new, healthy mitochondria and get 10% off of Mitopure. Head to timelinenutrition.com/drhyman and use code DRHYMAN10 at checkout. Right now, Levels is offering an additional two free months of their annual membership. Head over to levels.link/HYMAN to learn more. You can get 10% off Super Simple Grassfed Protein with the code protein10 at drhyman.com/protein. Full-length episodes (and corresponding links) of these interviews can be found here: Dr. Elizabeth Boham Dr. Mark Hyman  Dr. Robert Lustig Shawn Stevenson Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Rupa University, Pique, and Super Simple Grassfed Protein. Our gut bacteria regulate many of our bodily functions, from creating vitamins to regulating our immune system, our brain function, and of course, our metabolism and weight. They are critical to our long-term health. One such bacteria is Akkermansia muciniphila, which accounts for 1%–5% of our gut microbiome—or at least it’s supposed to!  In today’s episode of my series I’m calling Health Bites, I dive into Akkermansia—what it is, what role it plays in chronic disease prevention, and what you can do to increase it. This episode is brought to you by Rupa University, Pique, and Super Simple Grassfed Protein. If you’re a healthcare provider who wants to learn more about Functional Medicine testing, go to rupauniversity.com to sign up for a free live class or a boot camp! For a limited time, get up to 12% off plus an exclusive gift on Pique’s Fasting Tea bundle. Just go to Piquelife.com/farmacyfasting today. Right now, you can get 10% off Super Simple Grassfed Protein by heading to drhyman.com/protein and using code protein10. Here are more details from our interview (audio version / Apple Subscriber version): Healing my own gut and recovering my health (4:12 / 2:46)  What is Akkermansia, and how does it work? (7:54 / 5:12)  Akkermansia and chronic disease prevention (13:48 / 11:46) Foods that increase Akkermansia (24:26 / 22:20) Mentioned in this episode Pendulum Akkermansia Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Rupa Health, ButcherBox, ARMRA Colostrum, and Apollo. So many of us struggle with relationships. In fact, our relationships determine the quality of our life more than anything else. Unfortunately, the relationships many of us grew up around–and might consider “normal”--are, in fact, dysfunctional, creating a negative cycle we often don’t even realize we’re in.  Today on The Doctor’s Farmacy, I’m excited to talk to Nedra Tawwab about how to identify dysfunctional patterns in our relationships and what we can do to break the cycle and move forward. Nedra Glover Tawwab is the author of the New York Times bestsellers Drama Free and Set Boundaries, Find Peace. A licensed therapist and sought-after relationship expert, she has practiced relationship therapy for more than fifteen years. Nedra has appeared as an expert on Red Table Talk, The Breakfast Club, Good Morning America, and CBS Morning Show to name a few. Her work has been highlighted in The New York Times, The Guardian, and Vice, and has appeared on numerous podcasts, including The School of Greatness, We Can Do Hard Things, and Ten Percent Happier. Nedra runs a popular Instagram account where she shares practices, tools, and reflections for mental health and relationships.  This episode is brought to you by Rupa Health, ButcherBox, ARMRA Colostrum, and Apollo. ​​Access more than 3,000 specialty lab tests with Rupa Health. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com today. For new members of ButcherBox, you can receive New York Strip Steaks for a year PLUS $20 off your first order. Go to Butcherbox.com/farmacy and use code FARMACY. Receive 15% off your first order of ARMRA Colostrum. Go to tryarmra.com/MARK or enter MARK to get 15% off your first order. Visit apolloneuro.com/drhyman to save $40 on Apollo's wearable device. Here are more details from our interview (audio version / Apple Subscriber version): Setting boundaries as a people-pleaser (5:35 / 2:45) How to recognize and unlearn family dysfunction (8:13 / 6:17)   How childhood trauma impacts adult relationships (15:27 / 13:12) Changing relationships by setting boundaries (18:54 / 16:30)  The connection between sleep issues and relationship issues (26:26 / 22:40)  Tools for shifting our relationships and patterns (28:38 / 24:41) Toxic forgiveness (36:17 / 32:20) Impacting change in others (58:45 / 52:08)   Breaking family patterns in parenting (1:00:48 / 57:23)  Learn more at nedratawwab.com and @nedratawwab. Get a copy of Drama Free: A Guide to Managing Unhealthy Family Relationships. Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Rupa Health, AG1, HigherDOSE, and Super Simple Grassfed Protein.  We all know that life gets busy, but to stay healthy, you have to have a set of nonnegotiables that you make time for daily. Prioritizing food as medicine, establishing a consistent sleep routine, and cultivating community can all offer immense benefits, not only for your quality of life but your overall health and well-being too. In today’s episode, I talk with Dhru Purohit and Radha Agrawal about these three things that you can choose to focus on to level up your health. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. Radha Agrawal is the cofounder, CEO, and Chief Community Architect of Daybreaker, the early-morning dance and wellness movement. Daybreaker currently holds events in 25 cities and more than a dozen college campuses around the world and has a community of almost half a million people. She is also the author of a new book called Belong: Find Your People, Create Community, and Live a More Connected Life. In this episode, Radha makes a case for community. This episode is brought to you by Rupa Health, AG1, HigherDOSE, and Super Simple Grassfed Protein.  Rupa Health is a place where Functional Medicine practitioners can access more than 3,000 specialty lab tests from over 35 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. AG1 contains 75 high-quality vitamins, minerals, whole-food-sourced superfoods, probiotics, and adaptogens to support your entire body. Right now, AG1 is offering 10 FREE travel packs with your first purchase by visiting drinkAG1.com/HYMAN. Elevate your wellness game today by going to HigherDOSE.com. You can use promo code HYMAN at checkout to save 15% off site-wide or just go to HigherDOSE.com/hyman. Right now, you can get 10% off Super Simple Grassfed Protein with the code protein10 at drhyman.com/protein. Full-length episodes (and corresponding links) of these interviews can be found here: Dhru Purohit “How To Use Food As Medicine” Dhru Purohit “Why Sleep is More Important Than Diet” Radha Agrawal “The Most Important Medicine For Your Health and Longevity” Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Rupa Health and AG1. One key area of focus on your health you may not have thought to pay attention to is the dangers of advanced glycation end products. In fact, you may not have even been aware of their existence at all. Advanced glycation end products (AGEs for short) are compounds that can form when you cook food at high temperatures. Depending on your diet and overall health, they can start to build up in your body, which can be a big problem since they've been linked to a range of health problems from diabetes to cardiovascular disease. In today’s episode of my series I’m calling Health Bites, I dive into the science behind AGEs and what you can do to protect yourself from their deleterious effects. This episode is brought to you by Rupa Health and AG1. Rupa Health is a place where Functional Medicine practitioners can access more than 3,000 specialty lab tests from over 35 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now, AG1 is offering 10 FREE travel packs with your first purchase by visiting drinkAG1.com/HYMAN. Here are more details from our interview (audio version / Apple Subscriber version): What are advanced glycation end products? (3:57 / 1:38) Where do AGEs come from? (5:59 / 2:56)  Why AGEs are so bad (8:40 / 6:17) Reducing your AGE intake (9:19 / 6:56) Mentioned in this episode The 10-Day Detox Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Rupa Health, BiOptimizers, Sensate, and Zero Acre. Hidden inflammation is at the root of all chronic illness—conditions like heart disease, obesity, diabetes, dementia, depression, and cancer. So if inflammation is at the root of most modern diseases, how do we find the causes and get the body back in balance? Today on The Doctor’s Farmacy, I’m excited to talk to Dr. Shilpa Ravella about what is driving our epidemic of inflammation and inflammaging, why it plagues so many people, and what we can do to combat it.  Dr. Ravella is a gastroenterologist and Assistant Professor of Medicine at Columbia University Medical Center. She is the author of A Silent Fire: The Story of Inflammation, Diet & Disease, which investigates inflammation—the hidden force at the heart of modern disease. Her writing has appeared in The Atlantic, New York Magazine, The Wall Street Journal, TIME, Slate, Discover, and USA Today, among other publications.  This episode is brought to you by Rupa Health, BiOptimizers, Sensate, and Zero Acre. Rupa Health is a place where Functional Medicine practitioners can access more than 3,000 specialty lab tests from over 35 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. This month only you can get a FREE bottle of BiOptimizers’ full-spectrum magnesium supplement. To get your free bottle just go to magbreakthrough.com/hymanfree and enter coupon code hyman10. That’s it! I love my Sensate device. Whenever I use it, my mind calms down and I find myself getting more and better-quality sleep. Head on over to getsensate.com/Farmacy and use code FARMACY to get 10% off your Sensate device today. Zero Acre Oil is an all-purpose cooking oil with more healthy monounsaturated fat and significantly less inflammatory omega-6 fat than even avocado or olive oil. Go to zeroacre.com/MARK or use code MARK to redeem an exclusive offer. Here are more details from our interview (audio version / Apple Subscriber version): Helpful and harmful inflammation (5:18 / 2:46) How to know if you’re inflamed (7:37 / 4:46)  Diagnostic testing to assess inflammation (10:11 / 9:00)  What is driving our chronic inflammation? (14:59 / 12:42)  The health of our gut microbiome and inflammation (20:17 / 17:47) Stress, loneliness, and inflammation (25:44 / 21:47)  How environmental toxins drive inflammation (27:56 / 23:57)  The rise in food allergies and sensitivities (30:30 / 26:59) Reducing inflammation in the body (38:06 / 33:34)  Anti-inflammatory foods and supplements (49:52 / 45:30)  Get a copy of A Silent Fire: The Story of Inflammation, Diet & Disease. Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by AG1, Pendulum, BiOptimizers, and Super Simple Grassfed Protein.   If we were to identify one big lever to pull to improve global health, create economic abundance, restore environmental health, and reverse climate change, it would be transforming our entire food system. The policies and industry interests that drive our current system must change to fix our broken food system from field to fork and beyond. In today’s episode, I talk with Calley Means, Robby Sansom, Taylor Collins, and Dhru Purohit about industry funding that influences the results of food studies, marketing, and government policy. Calley Means is the cofounder of TrueMed, a company that enables Americans to buy exercise equipment and healthy food with FSA/HSA dollars. He is also the coauthor (with his sister, Dr. Casey Means) of an upcoming book on food as medicine. Earlier in his career, he was a consultant for food and pharma companies; he is now exposing the practices they use to weaponize our institutions of trust. Robby Sansom is cofounder and CEO at Force of Nature, a regeneratively sourced meat company based in Austin, TX. Force of Nature works in partnership with land stewards, ranchers, and farmers committed to creating a positive return on the planet. Robby is also a land steward at ROAM Ranch, where he owns regeneratively managed bison. Taylor Collins is the Chief Bison Wrangler and a cofounder at Force of Nature. In 2017, Taylor and his family purchased ROAM Ranch, a 900-acre multispecies regenerative ecosystem. Within five years of management, the ranch has seen dramatic improvements in soil carbon, water infiltration, plant diversity, and soil health. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. This episode is brought to you by AG1, Pendulum, BiOptimizers, and Super Simple Grassfed Protein.  Right now, AG1 is offering 10 FREE travel packs with your first purchase by visiting drinkAG1.com/HYMAN. Pendulum is offering my listeners 20% off their first month of an Akkermansia subscription with code HYMAN at Pendulumlife.com. This month only you can get a FREE bottle of BiOptimizers’ full-spectrum magnesium supplement at magbreakthrough.com/hymanfree using coupon code hyman10. Get 10% off Super Simple Grassfed Protein with the code protein10 at drhyman.com/protein. Full-length episodes of these interviews can be found here: Calley Means Robby Sansom and Taylor Collins Dhru Purohit Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by ButcherBox, Beekeeper’s Naturals, and Super Simple Grassfed Protein.  There are a number of insults that attack our guts on a regular basis. Some of them, like our diet, we have control over, but others, like environmental toxins, will find us whether we want them to or not (although there are ways to limit our exposure). This has led to an onslaught of a condition known as “leaky gut,” which likely affects all of us to some degree. In today’s episode of my series I’m calling Health Bites, I talk about leaky gut—what it is, what causes it, and how to treat it. This episode is brought to you by ButcherBox, Beekeeper’s Naturals, and Super Simple Grassfed Protein.  Right now, new ButcherBox members can get New York strip steaks for a year PLUS $20 off their first order. Just go to Butcherbox.com/farmacy and use code FARMACY. Right now, Beekeeper’s Naturals is giving my community an exclusive offer. Just go to beekeepersnaturals.com/HYMAN and enter code “HYMAN” to get 20% off sitewide. Right now, you can get 10% off Super Simple Grassfed Protein with the code protein10 at drhyman.com/protein.  Here are more details from our interview (audio version / Apple Subscriber version): Diseases connected to our gut and microbiome (3:30 / 1:27)  What is leaky gut? (5:43 / 3:13) Causes of leaky gut (8:10 / 5:38) How to know if you have a leaky gut (12:02 / 8:49) Healing a leaky gut (13:09 / 9:58)  Mentioned in this episode EWG’s Clean Fifteen and Dirty Dozen  Leaky Gut Blog Posts Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Rupa Health, Mitopure, Apollo, and Cozy Earth. We live in a country that claims to be based on science, goodwill, and policies intended to help people. But in reality, these things are often heavily influenced and manipulated by industry, particularly Big Food, Big Pharma, and Big Ag, which have corrupted many institutions, politicians, professional associations, and research entities. And it has, unfortunately, led to mass confusion and illness in the public.  Today on The Doctor’s Farmacy, I’m excited to talk to Robert F. Kennedy Jr., candidate for President in 2024, and my longtime friend about the chronic disease epidemic and his vision for how we can change our food system, economy, environment, and public health outcomes. On April 19, Robert F. Kennedy, Jr. announced his candidacy for president of the United States. He has carried on his family’s legacy of public service by devoting himself to environmental causes and children’s welfare. He is the founder of the Waterkeeper Alliance—the world’s largest clean water advocacy group—and served as its longtime chairman and attorney. He then went on to found Children’s Health Defense, where he served as chairman and chief litigation counsel in its campaign to address childhood chronic disease and toxic exposures. As President, Kennedy will end the forever wars, clean up the government, restore the middle class, heal the divide, and tell Americans the truth.  This episode is brought to you by Rupa Health, Mitopure, Apollo, and Cozy Earth. Rupa Health is a place where Functional Medicine practitioners can access more than 3,000 specialty lab tests from over 35 labs. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Mitopure is the first and only clinically tested pure form of a natural gut metabolite called urolithin A that clears damaged mitochondria away from our cells and supports the growth of new, healthy mitochondria. Get 10% off at timelinenutrition.com/drhyman and use code DRHYMAN10 at checkout. You can check out the Apollo wearable and save $40 by visiting apolloneuro.com/drhyman. Right now, get 40% off your Cozy Earth sheets. Just head over to cozyearth.com and use code DRHYMAN. Here are more details from our interview (audio version / Apple Subscriber version): Media censorship and why Bobby is running for president (4:45 / 3:07) Why did the US have so many Covid deaths? (9:37 / 8:03)  Division in America (20:38 / 18:46)  The repeal of the Fairness Doctrine (24:26 / 22:46)  Addressing anti-vax and conspiracy theorist claims (32:20 / 28:22)   Challenges and nuances of vaccines (35:57 / 32:00)  Improving health in America (42:51 / 38:50)  How the pharmaceutical industry is harming Americans (44:25 / 41:18)  How Bobby keeps healthy (54:19 / 50:24)  Learn more at Kennedy24.com. Learn more about your ad choices. Visit megaphone.fm/adchoices

Hey podcast community, Dr. Mark here. My team and I are so excited to offer you a 7 Day Free trial of the Dr. Hyman+ subscription for Apple Podcast. For 7 days, you get access to all this and more entirely for free!  It's so easy to sign up. Just go click the Try Free button on the Doctor’s Farmacy Podcast page in Apple Podcast.  In this teaser episode, you’ll hear a preview of our latest Dr. Hyman+ Functional Medicine Deep Dive on nutrition and optimal aging with Dr. Chris D'Adamo. To learn more about the Institute of Functional Medicine, sign up for IFM’s newsletter: https://www.ifm.org/about/free-newsletter/. Want to hear the full episode? Subscribe now. With your 7 day free trial to Apple Podcast, you’ll gain access to audio versions of: - Ad-Free Doctor’s Farmacy Podcast episodes - Exclusive monthly Functional Medicine Deep Dives - Monthly Ask Mark Anything Episodes  - Bonus audio content exclusive to Dr. Hyman+ Trying to decide if the Dr. Hyman+ subscription for Apple Podcast is right for you?  Email my team at [email protected] with any questions you have.   Please note, Dr. Hyman+ subscription for Apple Podcast only includes Dr. Hyman+ in audio content. Sign up for the Institute of Functional Medicine (IFM) newsletter: https://www.ifm.org/about/free-newsletter/ Explore IFM membership options: https://discover.ifm.org/ifm-membership Listen to the Institute of Functional Medicine podcast, Pathways to Well-Being: https://info.ifm.org/podcasts Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Rupa Health, Levels, and ARMRA Colostrum.  In an ideal world where soils are rich and the air and water are pure, we would be able to get all of the vitamins and nutrients we need through diet alone. However, for most, that’s just not practical in our toxic world. In today’s episode, I talk with Dr. Michael Murray, Fred Provenza, Dan Kittredge, and Jeff Tkach about the symbiotic relationship between plants and soil and why supplements may be necessary to make up for the lack of nutrients in the foods we eat. Dr. Michael Murray is a doctor of naturopathy, a field of alternative medicine that seeks to harness the power of nature to prevent illness and achieve the highest level of health possible. He is the Chief Science Advisor for iHerb and the author of more than 30 books, including The Encyclopedia of Natural Medicine Third Edition and The Longevity Matrix. Fred Provenza is a professor emeritus of behavioral ecology in the Department of Wildland Resources at Utah State University. He is the author of three books, including Nourishment: What Animals Can Teach Us about Rediscovering Our Nutritional Wisdom; Foraging Behavior: Managing to Survive in a World of Change; and The Art & Science of Shepherding: Tapping the Wisdom of French Herders (co-written with Michel Meuret). Dan Kittredge has been an organic farmer for more than 30 years and is the founder and executive director of the Bionutrient Food Association, a nonprofit whose mission is to “increase quality in the food supply.” Out of these efforts the Real Food Campaign was born, which has engineered a prototype of a handheld consumer spectrometer designed to test nutrient density at point of purchase. Jeff Tkach serves as the Chief Impact Officer for the Rodale Institute. Jeff is responsible for expanding Rodale Institute’s global influence in healing people and the planet by unlocking the transformational power of regenerative organic agriculture. Jeff served on the Rodale Institute’s board of Directors in 2016, where he was instrumental in fostering relationships between the organization and business leaders in the organic food industry. This episode is brought to you by Rupa Health, Levels, and ARMRA Colostrum.  Rupa Health is a place where Functional Medicine practitioners can access more than 3,000 specialty lab tests from over 35 labs. Check out a free, live demo with a Q&A or create an account at RupaHealth.com. Levels is offering an additional two free months of their annual membership at levels.link/HYMAN. Receive 15% off your first order of ARMRA Colostrum at tryarmra.com/MARK or enter MARK to get 15% off. Find full-length episodes of these interviews (and mentioned references) here: Dr. Michael Murray Fred Provenza Dan Kittredge Jeff Tkach Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Rupa University and AG1. Unfortunately, while almost never diagnosed, vitamin D deficiency affects over half of the population and has been linked to many cancers, high blood pressure, heart disease, diabetes, depression, fibromyalgia, chronic muscle pain, bone loss, and autoimmune diseases like multiple sclerosis. Vitamin D is almost totally absent from our food supply, and vitamin D deficiencies are the hidden cause of so much suffering—yet it is so easy to treat.  In today’s episode of my series I’m calling Health Bites, I talk about vitamin D deficiency, share my top strategies for optimal sun safety this summer, and much more. This episode is brought to you by Rupa University and AG1. If you’re a healthcare provider who wants to learn more about Functional Medicine testing, you owe it to yourself to go check it out today. Go to rupauniversity.com to sign up for a free live class or a boot camp! AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now, AG1 is offering 10 FREE travel packs with your first purchase by visiting drinkAG1.com/HYMAN. Here are more details from our interview (audio version / Apple Subscriber version): Sun exposure, cancer, and oxidative stress (3:20 / 00:50) Why we need vitamin D (4:40 / 3:26)  Vitamin D deficiency (5:05 / 4:12)  Optimal vitamin D levels and doses (7:34 / 5:35)  How your body makes vitamin D (10:59 / 9:19) Supplementing with vitamin D (12:29 / 10:53)  Protecting your skin from the sun (14:25 / 12:46)  Strategies for optimal sun safety (16:20 / 15:03)  Mentioned in this episode EWG’s Guide to Sunscreen EWG’s Skin Deep Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Rupa Health, BiOptimizers, LMNT, and Apollo. There is powerful science behind how our beliefs inform our genetic expression. It’s not our genes alone that dictate our health outcomes, rather it’s the biology of belief that determines our destiny.  Today on The Doctor’s Farmacy, I’m excited to talk to Dr. Bruce Lipton about how exactly our thoughts determine our genetic expression, and how we can influence our health using our minds. Dr. Bruce Lipton is a stem cell biologist and author of the bestselling books, The Biology of Belief, Spontaneous Evolution, and The Honeymoon Effect. Dr. Lipton is the recipient of the prestigious Japanese Goi Peace Award and has been listed in the top 100 of “the world’s most spiritually influential people” by Briton’s Watkins Journal for the last 13 years. This episode is brought to you by Rupa Health, BiOptimizers, LMNT, and Apollo. Rupa Health is a place where Functional Medicine practitioners can access more than 3,000 specialty lab tests from over 35 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. This month only you can get a FREE bottle of Magnesium Breakthrough. Just go to magbreakthrough.com/hymanfree and enter coupon code hyman10. Right now LMNT is offering my listeners a free sample pack with any purchase. This is a great way to try all eight flavors or share LMNT with a friend. Get yours at DrinkLMNT.com/hyman today. Apollo was designed by neuroscientists and physicians to tap into your body's natural rhythms to bring calm and focus and restore equilibrium to your nervous system. You can check out the Apollo wearable and save $40 by visiting apolloneuro.com/drhyman. Here are more details from our interview (audio version / Apple Subscriber version): How Bruce came to understand the power of belief (4:50 / 2:00)  Genes are responsible for less than 1 percent of disease (10:54 / 8:45)  Our thoughts are turned into chemistry by the brain (14:59 / 12:33)  The power of negative thinking (17:04 / 15:00)  Genetic vs epigenetic control (22:15 / 18:45)  How environmental signals get into cells (25:23 / 23:10)  How our minds are programmed, even before birth (42:03 / 36:02)  The conscious vs subconscious mind (46:16 / 43:12)  Why genes are not the cause of most diseases (55:03 / 50:51 Ways to reshape your thinking (58:21 / 54:07)  Learn more at brucelipton.com. Learn more about your ad choices. Visit megaphone.fm/adchoices

Hey podcast community, Dr. Mark here. My team and I are so excited to offer you a 7 Day Free trial of the Dr. Hyman+ subscription for Apple Podcast. For 7 days, you get access to all this and more entirely for free!  It's so easy to sign up. Just go click the Try Free button on the Doctor’s Farmacy Podcast page in Apple Podcast.  In this teaser episode, you’ll hear a preview of our monthly Ask Mark Anything episode. Want to hear the full episode? Subscribe now. With your 7 day free trial to Apple Podcast, you’ll gain access to audio versions of: - Ad-Free Doctor’s Farmacy Podcast episodes - Exclusive monthly Functional Medicine Deep Dives - Monthly Ask Mark Anything Episodes  - Bonus audio content exclusive to Dr. Hyman+ Trying to decide if the Dr. Hyman+ subscription for Apple Podcast is right for you?  Email my team at [email protected] with any questions you have.   Please note, Dr. Hyman+ subscription for Apple Podcast does not include access to the Dr. Hyman+ site and only includes Dr. Hyman+ in audio content.  Mentioned in this episode Beeya Wellness  Beeya Wellness Youtube Beeya Newsletter Seed Cycling 101: The Ultimate Guide to Balancing Hormones  How to Eliminate PMS in 5 Simple Steps   Levels Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Rupa Health, ButcherBox, and HigherDOSE.  Not only is protein a vital component of healthy skeletal muscle, but it also is an essential lever in weight loss, stabilizing blood sugar, and reversing metabolic syndrome. And when it comes to animal-based protein, we can’t just say all meat is good or no meat is good; it’s a matter of what types and sources of proteins you’re eating and what the rest of your diet looks like too.  In today’s episode, I talk with Dr. Gabrielle Lyon, Dr. Stephan van Vliet, and Dr. Don Layman about how much protein we should eat, the effects of animal protein on the environment, the best protein sources, and more. Dr. Gabrielle Lyon is an integrative physician who completed her fellowship in nutritional sciences and geriatrics at Washington University, St. Louis. She is board certified in family medicine and completed her undergraduate work in human nutrition vitamin and mineral metabolism. Dr. Lyon works closely with current and retired special operations military operators as a part of the Task Force Dagger Foundation. Dr. Stephan van Vliet is a nutrition scientist with metabolomics expertise at the Center for Human Nutrition Studies at Utah State University. He routinely collaborates with farmers, ecologists, and agricultural scientists to study critical linkages between agricultural production methods, the nutrient density of food, and human health. His work has been published in The American Journal of Clinical Nutrition, Scientific Reports, The Journal of Nutrition, and The Journal of Physiology. Dr. Layman is a professor emeritus in the Department of Food Science & Human Nutrition at the University of Illinois at Urbana-Champaign. Dr. Layman earned his BS and MS degrees in chemistry at Illinois State University and his doctorate in human nutrition and biochemistry at the University of Minnesota. He is recognized for his research on protein and amino acids for muscle health related to athletic performance, obesity, diabetes, and cardiometabolic health. This episode is brought to you by Rupa Health, ButcherBox, and HigherDOSE.  Rupa Health is a place where Functional Medicine practitioners can access more than 3,000 specialty lab tests from over 35 labs. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Right now, new ButcherBox members can get New York strip steaks for a year PLUS $20 off their first order. Just go to Butcherbox.com/farmacy and use code FARMACY. Elevate your wellness game today by going to HigherDOSE.com. You can use promo code HYMAN at checkout to save 15% site-wide or just go to HigherDOSE.com/hyman. Full-length episodes of these interviews (and links to all the references mentioned) can be found here: Dr. Gabrielle Lyon Dr. Stephan van Vliet Dr. Don Layman Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Rupa Health and Joovv. Mercury enters our bodies from many different sources, including mercury vapors in ambient air, ingestion via drinking water, fish, dental amalgams, occupational exposures, home exposures, over-the-counter products, and more. There’s no doubt about it: mercury is the most alarming, disease-causing source of environmental toxicity that I see daily in my practice.  In today’s episode of my series I’m calling Health Bites, I share my own experience with mercury issues and give you a comprehensive plan for reducing your exposure and healing from mercury toxicity.  This episode is brought to you by Rupa Health and Joovv. Rupa Health is a place where Functional Medicine practitioners can access more than 3,000 specialty lab tests from over 35 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. For a limited time, you’ll get an exclusive discount on Joovv’s Generation 3.0 devices (some exclusions do apply). Just go to Joovv.com/farmacy and use the code FARMACY. Here are more details from our interview (audio version / Apple Subscriber version): How I developed mercury toxicity (3:43 / 1:42)  The conventional medicine approach to treating mercury toxicity (5:34 / 3:33)  What I learned years ago at an international conference on mercury (6:09 / 4:07)  Testing mercury levels (10:06 / 8:04)  Sources of mercury (11:21 / 9:51)  Symptoms of mercury poisoning (14:30 / 12:30)  Mercury toxicity and dental fillings (15:33 / 13:31)  What does genetics have to do with mercury toxicity? (19:54 / 17:53)  Summary (22:12 / 20:12)  Mentioned in this episode The International Academy of Oral Medicine and Toxicology (IAOMT) Mercury in Fish Wallet Card EWG’s Consumer Guide to Seafood Monterey Bay Aquarium Seafood Watch Seatopia.fish Find a Functional Medicine Practitioner Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Rupa Health, Mitopure, Sunlighten, and Thrive Market. As we age, our body’s natural antioxidant defenses slow down, driving chronic inflammation and diminishing overall health.  To combat inflammaging, scientists have been studying compounds that can reduce inflammation and oxidative stress in the body. One such compound is astaxanthin, a powerful, naturally occurring antioxidant with profound anti-inflammatory health benefits. Today on The Doctor’s Farmacy, I’m excited to talk to David M. Watumull all about astaxanthin and how it helps to combat some of the key hallmarks of aging—inflammaging, mitochondrial dysfunction, and cell signaling. David M. Watumull has more than twenty years of experience in product development, commercialization, and business management related to astaxanthin—a safe and powerful, naturally-occurring anti-inflammatory—for human health. He is the co-founder and CEO of AX3 Life, a consumer longevity company formed to help people be their best selves longer. AX3 Life targets inflammaging—a core hallmark of aging—at its source with AX3 bio-pure astaxanthin. He is also the COO of Cardax, a life sciences business focused on advancing pharmaceutical and nutraceutical applications of astaxanthin. This episode is brought to you by Rupa Health, Mitopure, Sunlighten, and Thrive Market. Rupa Health is a place where Functional Medicine practitioners can access more than 3,000 specialty lab tests from over 35 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Mitopure is the first and only clinically tested pure form of a natural gut metabolite called urolithin A that clears damaged mitochondria away from our cells and supports the growth of new healthy mitochondria. Get 10% off at timelinenutrition.com/drhyman and use code DRHYMAN10 at checkout. When it comes to infrared saunas, my number one brand is Sunlighten. Right now, you can save up to $600 on your purchase. Simply visit Sunlighten.com/mark-hyman and mention my name, Dr. Hyman, to save. Thrive Market is offering 30% off your first order and a free gift worth up to $60 if you sign up now at thrivemarket.com/Hyman. Here are more details from our interview (audio version / Apple Subscriber version): Steps to reduce and manage oxidative stress and inflammation (4:18 / 2:25)  How astaxanthin targets key hallmarks of aging (7:02 /  4:35)  Life span benefits of astaxanthin (13:34 / 11:32)  How astaxanthin benefits joint, muscle, and cardiovascular health and cognitive function (15:09 / 13:26)  Where astaxanthin is found in nature (22:38 /  18:47)  The FOXO3 gene (27:54 / 24:05)  Astaxanthin for longevity and healthy aging (37:23 / 34:45)  Synthetic vs natural astaxanthin (39:54 / 36:03)  Learn more about the astaxanthin supplement AX3. Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Paleovalley, AG1, and Bioptimizers.  Difficult times and experiences happen to all of us. They can often leave us not feeling good enough, not feeling worthy of love, not being able to trust others, and more. And it can be easy to put self-care on the back burner, even when we know we need to face our struggles. Yet, when we make the time to be radically honest with ourselves, sit with our discomforts, and take action to change our state, we open up the door to healing. In today’s episode, I talk with Mel Robbins, Yung Pueblo, and Lewis Howes about how small actions we make every day can be the key to big changes that transform our lives. A New York Times bestselling author and self-publishing phenom, Mel Robbins’ work includes The High 5 Habit, The 5 Second Rule, and the number one-ranking The Mel Robbins Podcast. Her female-led media company produces provocative, life-changing content, with millions of books sold, billions of video views, six bestselling audiobooks, and one of the most viewed TEDx talks in the world. Her work has been translated into 41 languages and has changed the lives of millions of people worldwide. Diego Perez—who is widely known on Instagram and various social media networks by his pen name, Yung Pueblo—is a meditator and New York Times bestselling author. He has an online audience of nearly 3 million people. His writing focuses on the power of self-healing, creating healthy relationships, and the wisdom that comes when we truly work on knowing ourselves. His books include Inward, Clarity & Connection, and his most recent, Lighter, which was an instant New York Times bestseller. Lewis Howes is a New York Times bestselling author, keynote speaker, and industry-leading show host. Lewis is a two-sport All-American athlete, former professional football player, and member of the US men’s national handball team. His show The School of Greatness is one of the top podcasts in the world, with over 500 million downloads. He was recognized by the White House and President Obama as one of the top 100 entrepreneurs in the country under 30. This episode is brought to you by Paleovalley, AG1, and Bioptimizers.  Paleovalley is offering my listeners 15% off your entire first order. Just go to paleovalley.com/hyman. Right now, AG1 is offering 10 FREE travel packs with your first purchase by visiting drinkAG1.com/HYMAN. This month only you can get a FREE bottle of Magnesium Breakthrough. Just go to magbreakthrough.com/hymanfree and enter coupon code hyman10. Full-length episodes of these interviews (and links to all the references mentioned) can be found here: Mel Robbins Yung Pueblo Lewis Howes Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Rupa University and AG1. Gut health literally affects your entire body. Your gut houses 500 species and three pounds of bacteria. Too many bad gut flora (including parasites and yeast) or not enough good ones can spell serious trouble for your health. This is why if you want to fix your health, start with your gut. In today’s episode of my series I’m calling Health Bites, I talk about how you can heal many skin issues by changing your diet, optimizing your nutrient status, and healing your gut. This episode is brought to you by Rupa University and AG1. If you’re a healthcare provider who wants to learn more about Functional Medicine testing, you owe it to yourself to go check it out today. Go to rupauniversity.com to sign up for a free live class or a boot camp! AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now, AG1 is offering 10 FREE travel packs with your first purchase by visiting drinkAG1.com/HYMAN. Here are more details from our interview (audio version / Apple Subscriber version): The secret to healthy skin (3:18 / 1:00)  How I healed my own skin issues (3:31 / 1:56)  The conventional medicine approach to treating skin conditions (4:32 / 2:57)  How diet can affect your skin and overall health (6:20 / 4:15)  The Functional Medicine approach to skin health (6:56 / 5:17)  Strategies for optimal skin health (8:15 / 6:34)  Mentioned in this episode How to Tend to Your Inner Garden – Why Your Gut Flora May be Making You Sick UltraCalm: A 6-Step Plan to Reduce Stress and Eliminate Anxiety Environmental Working Group Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Rupa Health, BiOptimizers, Levels, and Cozy Earth.  We often hear the argument that in order to solve climate change we need to stop eating meat, but the truth is that animal agriculture done right is actually part of the solution. On today’s episode, I’m excited to talk to Robby Sansom and Taylor Collins about the nuances of regeneratively raised meat and how it can reverse climate change, support better health for those who eat it, and provide natural and caring conditions for the animals it involves.  Robby Sansom is Co-Founder & CEO at Force of Nature, a regeneratively sourced meat company based in Austin, TX. Previously, as CFO/COO at EPIC, Robby spent much of the last decade studying regenerative agriculture at ranches all over the world. Force of Nature works in partnership with land stewards, ranchers, and farmers committed to creating a positive return on the planet. Robby is also a land steward at ROAM Ranch, where he owns regeneratively managed bison. Taylor Collins is the Chief Bison Wrangler and a Co-founder of Force of Nature. In 2017, Taylor and his family purchased ROAM Ranch, a 900-acre multi-species regenerative ecosystem. Within 5 years of management, the ranch has seen dramatic improvements in soil carbon, water infiltration, plant diversity, and soil health. This episode is brought to you by Rupa Health, BiOptimizers, Levels, and Cozy Earth. Rupa Health is a place where Functional Medicine practitioners can access more than 3,000 specialty lab tests from over 35 labs. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. This month only you can get a FREE bottle of Magnesium Breakthrough. Just go to magbreakthrough.com/hymanfree and enter coupon code hyman10. Levels is offering an additional two free months of their annual membership. Learn more at levels.link/HYMAN. Get 40% off your Cozy Earth sheets. Just head over to cozyearth.com and use code MARK40. Here are more details from our interview (audio version / Apple Subscriber version): Big-picture issues with our food system (7:48 / 5:30)  Regenerative agriculture as a solution to these issues (11:23 / 9:11)  How the food industry takes advantage of consumers (13:21 / 11:54)  The true cost of corn (19:41 / 17:25)  My visit to Roam Ranch (23:55 / 19:37)  The nutritional value of regenerative bison vs feedlot beef (42:32 / 37:38)  Learnings from a regenerative rancher (45:15 / 42:17)  Six principles of soil health (54:41 / 50:26)  Food production around the world (1:01:51 / 56:56)   Is regenerative agriculture scalable on a global level? (1:05:47 / 1:01:20) Learn more at Roamranch.com and Forceofnature.com. Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Rupa Health, InsideTracker, and Wonderfeel.  Women in midlife often experience night sweats, mood swings, and other uncomfortable and difficult symptoms resulting from hormonal shifts. This is also often a time of significant stressors, as many women are juggling parenting, a career, and even caring for elders. And contrary to popular belief, women cannot follow the same health and fitness protocols as men and expect to see the same results. In today’s episode, I talk with Dr. Mindy Pelz, Dr. Izabella Wentz, and Cynthia Thurlow about things women over 40 can do to ease their experiences during perimenopause and menopause. Dr. Mindy Pelz is a renowned holistic health expert and one of the leading voices in educating women about their hormonal health. She has empowered hundreds of thousands of people around the world to tap into their bodies' innate healing abilities through her “5-Step Approach,” which uses fasting, personalized nutrition, stress management, chemical detoxification, and lifestyle changes to optimize health and slow the aging process. Dr. Izabella Wentz is an internationally acclaimed thyroid specialist and a licensed pharmacist who has dedicated her career to addressing the root causes of autoimmune thyroid disease after being diagnosed with Hashimoto’s thyroiditis in 2009. She is the author of three books on Hashimoto’s: Hashimoto’s Thyroiditis Lifestyle Interventions for Finding and Treating the Root Cause, Hashimoto’s Food Pharmacology, and Hashimoto’s Protocol. Her latest book is Adrenal Transformation Protocol: A 4-Week Plan to Release Stress Symptoms and Go from Surviving to Thriving. Cynthia Thurlow is a nurse practitioner, author of the bestselling book Intermittent Fasting Transformation, a two-time TEDx speaker, with her second talk having more than 14 million views, and the host of the Everyday Wellness podcast, a consistent top iTunes podcast in Nutrition. With over 20 years of experience in health and wellness, Cynthia is a globally recognized expert in intermittent fasting and women’s health and has been featured on ABC, FOX5, KTLA, CW, Medium, Entrepreneur, and The Megyn Kelly Show. This episode is brought to you by Rupa Health, InsideTracker, and Wonderfeel.  Rupa Health is a place where Functional Medicine practitioners can access more than 3,000 specialty lab tests. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. InsideTracker is offering my community 20% off at insidetracker.com/drhyman. Wonderfeel Youngr NMN works by increasing your levels of NAD, a critical molecule our bodies produce that we literally need to survive. Feel the wonder of innovation at getwonderfeel.com. Full-length episodes of these interviews (and links to all the references mentioned) can be found here: Dr. Mindy Pelz Dr. Izabella Wentz Cynthia Thurlow Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Rupa Health and HigherDOSE. Gut health literally affects your entire body. Your gut houses 500 species and three pounds of bacteria. Too many bad gut flora (including parasites and yeast) or not enough good ones can spell serious trouble for your health. This is why if you want to fix your health, start with your gut. In today’s episode of my series I’m calling Health Bites, I talk about the gut-immune and gut-brain connection, what imbalances our gut health, and my top strategies for reducing inflammation and healing the gut.  This episode is brought to you by Rupa Health and HigherDOSE. Rupa Health is a place where Functional Medicine practitioners can access more than 3,000 specialty lab tests from over 35 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Elevate your wellness game today by going to HigherDOSE.com. You can use promo code HYMAN at checkout to save 15% off site-wide or just go to HigherDOSE.com/hyman. Here are more details from our interview (audio version / Apple Subscriber version): Two primary ways the gut affects your health (5:05 / 3:06)  How your gut is connected to your immune system (5:38 / 3:37) Why healthy gut flora is crucial for optimal gut health (7:43 / 5:39)  How to positively influence your gut flora today (11:28 / 8:04)  Our second brain (11:40 / 9:41)  Causes of gut imbalances (14:14 / 12:12)  How to fix your gut (16:43 / 14:52)  Mentioned in this episode Gut-health blogs Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Rupa Health, ButcherBox, Pendulum, and Apollo. I don’t just want to live a long life, I want to feel good while I’m doing it.  That’s why I’m always interested in the latest therapies to slow the aging process. Stem cells are one of those therapies that have been gaining a lot of traction for reducing nerve and muscle pain, improving the appearance and health of hair and skin, and even increasing sexual vitality. Today on The Doctor’s Farmacy, I’m excited to talk to Dr. Bob Hariri about stem cell therapy and how it’s changing the field of aging science and the future of human health.  Dr. Bob Hariri is an accomplished surgeon, biomedical scientist, and serial entrepreneur in two technology sectors, biomedicine, and aerospace. He is the chairperson, founder, and chief executive officer of Celularity, Inc., one of the world’s leading human cellular therapeutics companies. Dr. Hariri pioneered the use of stem cells to treat a range of life-threatening human diseases. He holds over 170 issued and pending patents for discoveries, including placenta-derived stem cells, which Nature recognized as one of the ten most important patent estates in the field. He has authored over 150 published chapters, articles, and abstracts. This episode is brought to you by Rupa Health, ButcherBox, Pendulum, and Apollo. Rupa Health is a place where Functional Medicine practitioners can access more than 3,000 specialty lab tests from over 35 labs. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Right now ButcherBox has a special offer: new members can get New York strip steaks for a year PLUS $20 off your first order at Butcherbox.com/farmacy with code FARMACY. Pendulum is offering my listeners 20% off their first month of an Akkermansia subscription with code HYMAN at Pendulumlife.com. Apollo was designed by neuroscientists and physicians to tap into your body's natural rhythms to bring calm and focus and restore equilibrium to your nervous system. You can check out the Apollo wearable and save $40 by visiting apolloneuro.com/drhyman. Here are more details from our interview (audio version / Apple Subscriber version): Three things people commonly do to shorten lifespan (6:07 / 3:40)  Why stem cells are so remarkable (10:20 / 7:52)  Retrieving and injecting stem cells into the body (15:07 / 12:40)  Embryonic and placental stem cells (19:47 / 16:46)  Capabilities of injected stem cells (28:14 / 24:12)  Reprogramming your biology for a younger you (35:50 / 31:20)  Cell therapies beyond stem cells (52:05 / 47:33)  Natural killer cells (55:28 / 50:54)  Tips for healthy aging (1:15:15 / 1:10)  Learn more at celularity.com and check out pilotinghealth.com. Learn more about your ad choices. Visit megaphone.fm/adchoices

Hey podcast community, Dr. Mark here. My team and I are so excited to offer you a 7 Day Free trial of the Dr. Hyman+ subscription for Apple Podcast. For 7 days, you get access to all this and more entirely for free!  It's so easy to sign up. Just go click the Try Free button on the Doctor’s Farmacy Podcast page in Apple Podcast.  In this teaser episode, you’ll hear a preview of our recent Ask Ask A Nutritionist episode with Lisa Dreher. Want to hear the full episode? Subscribe now. With your 7 day free trial to Apple Podcast, you’ll gain access to audio versions of: - Ad-Free Doctor’s Farmacy Podcast episodes - Exclusive monthly Functional Medicine Deep Dives - Monthly Ask Mark Anything Episodes  - Bonus audio content exclusive to Dr. Hyman+ Trying to decide if the Dr. Hyman+ subscription for Apple Podcast is right for you?  Email my team at [email protected] with any questions you have.   Please note, Dr. Hyman+ subscription for Apple Podcast does not include access to the Dr. Hyman+ site and only includes Dr. Hyman+ in audio content.  Resources Is there such a thing as Anti-Nutrients? Lisa’s Thoughts on Lectins To Gluten or Not to Gluten Macular Support Supplement Iron chelate Klaire Labs Proferrin What happens when you stop eating bread and gluten? Natural Medicines Database Pure Encapsulations Magnesium Glycinate Mag SRT B-Free UltraWellness Center Nutrition Services WeNatal Prenatal Supplements Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Paleovalley, AG1, and Mitopure.  Many people still believe that eating cholesterol and fat, especially saturated fat, causes heart attacks and that taking statin drugs is the only way to reduce your risk of heart attacks, but now we know the science says otherwise. The good news is this: we have a lot more control than we originally thought when it comes to preventing and reversing heart disease. In today’s episode, I talk with Dr. Cindy Geyer, Dr. Aseem Malhotra, and Dr. Todd LePine about why we need to look beyond cholesterol levels to protect our hearts. Dr. Cindy Geyer received her bachelor of science and doctor of medicine degrees, with honors, from the Ohio State University. She completed her residency in internal medicine at Strong Memorial Hospital in Rochester, NY, and is triple board certified in internal medicine, integrative medicine, and lifestyle medicine. She joined The UltraWellness Center in 2021 after practicing and serving as the medical director at Canyon Ranch for 23 years. Dr. Aseem Malhotra is an NHS-trained consultant cardiologist and visiting professor of evidence-based medicine at the Bahiana School of Medicine and Public Health in Salvador, Brazil. He is a founding member of Action on Sugar. He is a pioneer of the lifestyle medicine movement in the UK and in 2018 was ranked by software company Onalytica as the number one doctor in the world influencing obesity thinking. Dr. Malhotra's first book, The Pioppi Diet, coauthored with Donal O'Neill, was an international bestseller, and his next book, The 21-Day Immunity Plan, was also a Sunday Times top 10 bestseller. His new book is A Statin-Free Life. Dr. Todd LePine graduated from Dartmouth Medical School and is board certified in internal medicine, specializing in Integrative Functional Medicine. He is an Institute for Functional Medicine Certified Practitioner. Prior to joining The UltraWellness Center, he worked as a physician at Canyon Ranch in Lenox, MA, for 10 years. His areas of interest include optimal aging, bio-detoxification, functional gastrointestinal health, systemic inflammation, autoimmune disorders, and the neurobiology of mood and cognitive disorders. This episode is brought to you by Paleovalley, AG1, and Mitopure.  Paleovalley is offering my listeners 15% off their entire first order. Just go to paleovalley.com/hyman to check out all their clean Paleo products and take advantage of this deal. Right now, AG1 is offering 10 FREE travel packs with your first purchase by visiting drinkAG1.com/HYMAN. Get 10% off Mitopure at timelinenutrition.com/drhyman and use code DRHYMAN10 at checkout. Full-length episodes of these interviews (and links to all the references mentioned) can be found here: Dr. Cindy Geyer Dr. Aseem Malhotra Dr. Todd LePine Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by ButcherBox and AG1. About 30 years ago, when I became seriously ill with chronic fatigue syndrome, I felt like I simultaneously had dementia, depression, and ADD. My brain felt broken! That’s when I discovered Functional Medicine. One huge benefit I experienced when I reversed my chronic fatigue syndrome was how well my brain improved. Over the years, I fine-tuned my approach for a sharper, faster, and better brain.  In today’s episode of my series I’m calling Health Bites, I am talking about things that can lead to a broken brain and my top strategies for improving brain health.  This episode is brought to you by ButcherBox and Athletic Greens. When you sign up today, ButcherBox will send you two pounds of 100% grass-fed, grass-finished beef free in your first box plus $20 off. To receive this offer, go to ButcherBox.com/farmacy. AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now, Athletic Greens is offering 10 FREE travel packs with your first purchase by visiting drinkAG1.com/HYMAN. Here are more details from our interview (audio version / Apple Subscriber version): What leads to a broken brain? (5:36 / 3:00)  Fixing your brain starts with fixing your body (7:19 / 5:40)  Things that damage the brain (8:21 / 6:15)  Brain-boosting foods and supplements (10:51 / 7:43)  Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Rupa Health, BiOptimizers, Mitopure, and AquaTru. ⁣⁣NAD has been popping up everywhere, and for good reason. It’s a fundamental driver of our health and longevity, and we’re now learning how boosting NAD levels might offset and improve the effects of aging.  On today’s episode, I’m excited to talk to Dr. Andrew Salzman all about NAD—how it is a key component involved in mitochondrial production, and is a critical substrate for several enzymes, including sirtuins, which play key roles in healthy aging, weight management, metabolic syndrome, and metabolism. Dr. Salzman is a physician, inventor, professor, and biomedical entrepreneur. Dr. Salzman received his medical degree from Harvard University and has spent decades in drug discovery and development, raising over $165M in NIH grants for research. In addition to 50 patents, Dr. Salzman is credited with a breakthrough discovery in cellular DNA repair, which led to the world's first clinical application for successfully treating breast cancer caused by mutations in BRCA1 and BRCA2 genes. Millions of patients are benefiting from discoveries by Dr. Salzman in areas including mitochondrial health, gastrointestinal microbiota, damage caused by inflammation and oxidative stress to human cells and DNA, autoimmune disease, and cancer. This episode is brought to you by Rupa Health, BiOptimizers, Mitopure, and AquaTru. Rupa Health is a place where Functional Medicine practitioners can access more than 3,000 specialty lab tests from over 35 labs. You can check out a free, live demo with a Q&A or create an account a RupaHealth.com. BiOptimizers is offering my listeners 10% off Sleep Breakthrough. If you buy two or more you’ll get a free bottle of Magnesium Breakthrough. This is a limited-time offer. Go to sleepbreakthrough.com/hyman and use the code hyman10.  Get 10% off Mitopure at timelinenutrition.com/drhyman and use code DRHYMAN10 at checkout. Right now, my podcast listeners can access the AquaTru water filter for as low as $249. That’s $100 off the normal price. All you have to do is go to drhyman.com/filter, and you can get this special, exclusive price. Here are more details from our interview (audio version / Apple Subscriber version): How NAD helps us produce energy (5:00 / 3:04)  The science behind how NAD impacts health and longevity (10:08 / 8:15)  The role NAD plays in maintaining health (16:27 / 13:26)  NAD’s multiple functions (23:46 / 21:18)  Preserving NAD levels (30:34 / 27:47)  Where NAD is made in the body (34:53 / 30:35)   How NAD benefits sleep (41:17 / 37:04)  Do NMN and NAD cause cancer? (47:12 / 42:57)  Research on NMN in humans (50:23 / 46:07)  The difference between NMN and NR (1:00:54 / 51:55)  Learn more about Wonderfeel Youngr NMN. Learn more about your ad choices. Visit megaphone.fm/adchoices

Hey podcast community, Dr. Mark here. My team and I are so excited to offer you a 7 Day Free trial of the Dr. Hyman+ subscription for Apple Podcast. For 7 days, you get access to all this and more entirely for free! It's so easy to sign up. Just go click the Try Free button on the Doctor’s Farmacy Podcast page in Apple Podcast.  In this teaser episode, you’ll hear a preview of our monthly Ask Mark Anything episode. Want to hear the full episode? Subscribe now. With your 7 day free trial to Apple Podcast, you’ll gain access to audio versions of: - Ad-Free Doctor’s Farmacy Podcast episodes - Exclusive monthly Functional Medicine Deep Dives - Monthly Ask Mark Anything Episodes  - Bonus audio content exclusive to Dr. Hyman+ Trying to decide if the Dr. Hyman+ subscription for Apple Podcast is right for you? Email my team at [email protected] with any questions you have.   Please note, Dr. Hyman+ subscription for Apple Podcast does not include access to the Dr. Hyman+ site and only includes Dr. Hyman+ in audio content.  Mentioned in this episode ROOT by Hudson Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Rupa Health, AG1, Pique, and Joovv.  While our body's detoxification systems are sophisticated and well functioning, they are not far enough evolved to protect us fully from the toxic burdens we encounter in our environment. In today’s episode, I talk with Dave Asprey, Dr. Todd LePine, and Dhru Purohit about environmental contaminants that could be lurking behind your persistent health symptoms and why testing should be an integral part of our routine health exams as we age. Dave Asprey is an entrepreneur, the “Father of Biohacking,” and the leading voice in the movement to take control of your own biology. He’s hosted over 1,000 episodes of The Human Upgrade podcast (formerly Bulletproof Radio) for more than a decade. He also hosts the world’s largest and longest-running biohacking conference. He’s a New York Times bestselling author of multiple books, creator of Danger Coffee and Bulletproof Coffee, and owner and CEO of Upgrade Labs, the world’s first Human Upgrade Center. Dr. Todd LePine graduated from Dartmouth Medical School and is board certified in internal medicine, specializing in integrative Functional Medicine. He is an Institute for Functional Medicine Certified Practitioner. Prior to joining The UltraWellness Center, he worked as a physician at Canyon Ranch in Lenox, MA, for 10 years. His areas of interest include optimal aging, bio-detoxification, functional gastrointestinal health, systemic inflammation, autoimmune disorders, and the neurobiology of mood and cognitive disorders. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. This episode is brought to you by Rupa Health, Athletic Greens, Pique, and Joovv.  Rupa Health is a place where Functional Medicine practitioners can access more than 3,000 specialty lab tests from over 35 labs. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Right now, Athletic Greens is offering 10 FREE travel packs of AG1 with your first purchase at drinkAG1.com/HYMAN. For a limited time, get up to 12% off plus an exclusive gift on Pique’s Fasting Tea bundle at Piquelife.com/farmacyfasting. For a limited time, you’ll get an exclusive discount on Joovv’s Generation 3.0 devices (some exclusions do apply). Just go to Joovv.com/farmacy and use the code FARMACY. Full-length episodes of these interviews (and links to references mentioned) can be found here: Dave Asprey Dr. Todd LePine Dhru Purohit Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Rupa Health and Levels. What matters most in life is the quality of our experiences and the ability to be awake to what is real and true in our lives for both the difficult and the happy times. But that is harder than it sounds. More and more, we struggle with attention and focus. In today’s episode of my series I’m calling Health Bites, I discuss why we are so easily distracted, my own journey into meditation, and the incredible health benefits of a regular meditation practice. This episode is brought to you by Rupa Health and Levels. Rupa Health is a place where Functional Medicine practitioners can access more than 3,000 specialty lab tests from over 35 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. Levels provides real-time feedback on how diet and lifestyle choices impact your metabolic health. Right now, Levels is offering an additional two free months of their annual membership. Learn more at levels.link/HYMAN. Here are more details from our interview (audio version / Apple Subscriber version): Why are attention and focus so hard to come by? (4:35 / 2:20)  Training the mind (7:15 / 4:55)  Why I studied Buddhism in college (8:20 / 6:24)  My experience doing a silent meditation retreat (13:13 / 11:00)  The point of meditation and the benefits it offers (14:58 / 12:42) How to do a simple mindfulness meditation (17:51 / 15:15)  Mentioned in this episode Ziva Meditation Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Cozy Earth, Rupa Health, Apollo, and Wonderfeel. Over the years, it has become a widely held belief that cancer is predominately a genetic disease or simply the consequence of bad luck. An empowering evolution in cancer research, however, suggests we have far more control over our risk than previously thought.  I’m excited to talk to Dr. Thomas Seyfried about the underlying causes of cancer and why addressing metabolic dysfunction is a very important and often overlooked area of its prevention and treatment.  Dr. Thomas Seyfried is an American professor of biology, genetics, and biochemistry at Boston College. He received his Ph.D. from the University of Illinois Urbana-Champaign in 1976 and did his postdoctoral fellowship at the Yale University School of Medicine. Dr. Seyfried has over 150 peer-reviewed publications, and his research focuses primarily on the mechanisms driving cancer, epilepsy, and neurodegenerative diseases and calorie-restricted ketogenic diets in their prevention and treatment. He is the author of Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer and presently serves on the Nutrition & Metabolism, Neurochemical Research, Journal of Lipid Research, and ASN Neuro editorial boards. This episode is brought to you by Cozy Earth, Rupa Health, Apollo, and Wonderfeel. Get 40% off your Cozy Earth sheet at cozyearth.com and use code MARK40. Rupa Health is a place where Functional Medicine practitioners can access more than 3,000 specialty lab tests. Check out a free, live demo with a Q&A or create an account at RupaHealth.com. Apollo was designed by neuroscientists and physicians to tap into your body's natural rhythms to bring calm and focus and restore equilibrium to your nervous system. Check out the Apollo wearable and save $40 at apolloneuro.com/drhyman. Wonderfeel Youngr NMN works by increasing your levels of NAD, a critical molecule our bodies produce that we literally need to survive. Feel the wonder of innovation at getwonderfeel.com. Here are more details from our interview (audio version / Apple Subscriber version): How Dr. Seyfried’s work on treating epilepsy with a ketogenic diet informed his understanding of cancer (6:57 / 3:14)  Mitochondrial damage and cancer (16:58 / 14:44)  Glucose fermentation and oxidative stress and their links to cancer (25:52 / 24:47)  Our current misunderstanding of the cause of cancer (32:19 / 29:54)  Current cancer treatments vs metabolic oncology (38:31 / 36:50)  Populations without cancer incidence (56:10 / 51:55)  Metabolic cancer treatment for dogs (1:09:27 / 1:05:11)  Using a ketogenic diet with current cancer treatments (1:12:56 / 1:08:50)  Learn more at tomseyfried.com and at the Foundation for Metabolic Cancer Therapies. Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you b Rupa University, Paleovalley, HigherDOSE, and Athletic Greens.  There are many areas of life that we can dial in for optimal health and longevity. Three of those areas are what we eat, our quality of sleep, and our energy production. We eat pounds of food every single day that act as information for our cells and influence our DNA expression. When we sleep, our brain’s immune system (the glymphatic system) clears away damaged cells. And increasing our energy will not only help us feel better but will also support all the systems of the body to function better. In today’s episode, I talk with Dhru Purohit in my Masterclass series about the Functional Medicine approach to food, improving our sleep, and powering up our bodies. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. This episode is brought to you by Rupa University, Paleovalley, HigherDOSE, and Athletic Greens.  If you’re a healthcare provider who wants to learn more about Functional Medicine testing, you owe it to yourself to go check it out today. Go to rupauniversity.com to sign up for a free live class or a boot camp! Paleovalley is offering my listeners 15% off their entire first order. Just go to paleovalley.com/hyman to check out all their clean Paleo products and take advantage of this deal. Elevate your wellness game today by going to HigherDOSE.com. You can use promo code HYMAN at checkout to save 15% off site-wide or just go to HigherDOSE.com/hyman. AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now, Athletic Greens is offering 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Full-length episodes of these interviews (and all referenced show notes) can be found here: How to Use Food As Medicine Daily Steps to Boost Energy and Never Be Tired Again Why Sleep is More Important Than Diet—Optimize it Today Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by BiOptimizers and Athletic Greens. Taking care of yourself, practicing self-love and self-compassion, working on a growth mindset, building relationships and community, and having a sense of purpose are all crucial to living a fulfilling, long, healthy life. Your thoughts, feelings, and beliefs are all transmuted into biological signals that change your gene expression, impacting your immune function, hormones, microbiome, neurotransmitters, neuroplasticity, mitochondria, and more. Yet many of us tend to put self-care last on our list of to-dos (I certainly have for much of my life, to the detriment of my own health). In today’s episode of my series I’m calling Health Bites, I share my strategies for prioritizing self-care for a healthy mind and spirit. This episode is brought to you by BiOptimizers and Athletic Greens. BiOptimizers is offering my listeners 10% off Sleep Breakthrough. If you buy two or more you’ll get a free bottle of Magnesium Breakthrough. This is a limited-time offer. Go to sleepbreakthrough.com/hyman and use the code hyman10. AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now, Athletic Greens is offering 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman. Here are more details from our interview (audio version / Apple Subscriber version): Learnings from the Blue Zones (4:00 / 1:10)  How your thoughts, feelings, and beliefs impact your health (4:44 / 1:55)  The health benefits of self-compassion and social connections (6:43 / 3:54)  The importance of mindset and having a sense of purpose (8:35 / 5:48)  Simple ways to prioritize self-care and reset our stress response (12:23 / 9:39) Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Rupa Health, Mitopure, Nordic Naturals, and Apollo. We are a culture obsessed with happiness, except we’ve been going about it all wrong. Before I became a doctor, I actually studied Buddhism. I wanted to understand the root of human suffering, and through that, understand the way to create happiness.  On today’s episode, I’m excited to talk to Dan Harris about the science of happiness, how to deal with the challenges of modern-day life, and how to create more happiness for ourselves and for those around us.  Dan Harris is an author, podcaster, and entrepreneur. For 21 years, he worked as an anchor and correspondent for ABC News, hosting such shows as Nightline and the weekend editions of Good Morning America. Dan has reported from all over the planet, covering wars in Afghanistan and Iraq and producing investigative reports in Haiti, Cambodia, and the Amazon. After having a nationally televised panic attack on Good Morning America, Dan discovered meditation and then wrote the best-selling book 10% Happier as a way to encourage fellow skeptics to give the practice a shot. After that first book, Dan launched the Ten Percent Happier app, wrote a second book, and started the Ten Percent Happier podcast, where he interviews celebrities, entrepreneurs, authors, scientists, and meditation teachers about how to do life better. This episode is brought to you by Rupa Health, Mitopure, Nordic Naturals, and Apollo. Rupa Health is a place where Functional Medicine practitioners can access more than 3,000 specialty lab tests. Check out a free, live demo with a Q&A or create an account at RupaHealth.com. Get 10% off Mitopure at timelinenutrition.com/drhyman and use code DRHYMAN10 at checkout. Shop Nordic Naturals omegas today at nordic.com and save 20% using code FARMACY. Check out the Apollo wearable and save $40 by visiting apolloneuro.com/drhyman. Here are more details from our interview (audio version / Apple Subscriber version): The misinterpretation of an incident with the Dalai Lama shown in a recent viral video (2:28 / 00:50)  How to be happier and healthier (9:18 / 6:19)  Wise selfishness (16:34 / 14:15)  The neurobiology of altruism (20:19 / 18:06)  How to train your brain for happiness (26:01 / 21:44)  The connection between psychedelics and meditation (33:31 / 29:02)  How Dan’s life has changed from meditation (37:25 / 33:47)  Meditation as one component of trauma therapy (57:40 / 53:19)  Self-criticism and judgment of others (1:01:02 / 56:34)  Dan’s experience spending time with the Dalai Lama (1:08:00 / 1:03:35) The Dalai Lama's Guide to Happiness podcast series and video challenge Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Rupa Health, InsideTracker, and LMNT. Compounds that have long been considered recreational drugs by conventional standards are finally being recognized through science as powerful tools for overcoming hard-to-treat health issues like PTSD, depression, addiction, and more. For the right person, psychedelics can provide a sense of peace and hope that helps heal their inner wounds and allows them to live with more freedom. In today’s episode, I talk with Rick Doblin, Alberto Villoldo, and Wade Davis about the ancient healing mechanisms of plant medicine. Rick Doblin, PhD, is the founder and executive director of the Multidisciplinary Association for Psychedelic Studies (MAPS). He received his doctorate in public policy from Harvard’s Kennedy School of Government. His professional goals are to help develop legal contexts for the beneficial uses of psychedelics and marijuana, primarily as prescription medicines but also for personal growth for otherwise healthy people, and eventually to become a legally licensed psychedelic therapist. Medical anthropologist Alberto Villoldo, PhD, is an international bestselling author who has researched the shamanic healing practices of the Amazon and Andes for over 25 years. He is the founder of the Four Winds Society, an organization dedicated to the bridging of ancient shamanic traditions with modern medicine and psychology. Wade Davis is a writer, photographer, and filmmaker. Explorer-in-Residence at the National Geographic Society from 2000 to 2013, he is currently Professor of Anthropology and the BC Leadership Chair in Cultures and Ecosystems at Risk at the University of British Columbia. He is the author of 23 books, including One River, The Wayfinders, and Into the Silence, and he was the winner of the 2012 Baillie Gifford Prize for Non-Fiction (formerly the Samuel Johnson Prize), the top nonfiction prize in the English language. This episode is brought to you by Rupa Health, InsideTracker, and LMNT.  Rupa Health is a place where Functional Medicine practitioners can access more than 3,000 specialty lab tests like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. InsideTracker is offering my community 20% off at insidetracker.com/drhyman. LMNT is offering my listeners a free sample pack with any purchase. Get yours at DrinkLMNT.com/hyman today. Full-length episodes of these interviews can be found here: Rick Doblin Alberto Villoldo Wade Davis Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Rupa Health and InsideTracker. We’ve become exposed to a greater number of environmental toxins than ever before. Environmental toxins can feed cancer, interfere with glucose and cholesterol metabolism, and induce insulin resistance and obesity through multiple mechanisms, including inflammation, oxidative stress, mitochondrial injury, altered thyroid metabolism, and impaired central appetite regulation.  In today’s episode of my series I’m calling Health Bites, we’re talking about how environmental toxins impact our health, the top endocrine-disrupting toxins, and my strategies for reducing your exposure. I also share which foods you should be sure to buy organic. This episode is brought to you by Rupa Health and InsideTracker. Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 35 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com. InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. Here are more details from our interview (audio version / Apple Subscriber version): How environmental toxins impact our health (3:46 / 00:58) The top endocrine-disrupting toxins (5:52 / 4:01) Strategies to reduce your toxic burden (10:41 / 8:49)  EWG’s Clean Fifteen and Dirty Dozen lists (16:02 / 15:00)  Mentioned in this episode EWG's Skin Deep Database EWG's Guide to Healthy Cleaning Thrive Market Seatopia.fish EWG’s 2023 Shopper’s Guide to Pesticides in Produce Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Cozy Earth, ButcherBox, BiOptimizers, and Levels. Contrary to popular belief, women cannot follow the same health and fitness protocols as men and expect to see the same results. Unlike men, women in their reproductive years have specific hormonal considerations, and their rise and fall throughout the month impact everything from energy to focus, mood, metabolism, and the ability to adapt to good-for-you stressors like exercise or fasting. On today’s episode, I’m excited to talk to Dr. Mindy Pelz all about the benefits of fasting and how women, in particular, can cultivate a fasting routine in a way that honors their hormones.  Dr. Mindy is a renowned holistic health expert and one of the leading voices in educating women about their hormonal health. She has empowered hundreds of thousands of people around the world to tap into their bodies' innate healing abilities through her “5-Step Approach,” which uses fasting, personalized nutrition, stress management, chemical detoxification, and lifestyle changes to optimize health and slow the aging process. This episode is brought to you by Cozy Earth, ButcherBox, BiOptimizers, and Levels. Cozy Earth makes the most comfortable, temperature-regulating, and nontoxic sheets on the market. Right now, get 40% off your Cozy Earth sheets. Just head over to cozyearth.com and use code MARK40. When you sign up today, ButcherBox will send you two pounds of 100% grass-fed, grass-finished beef free in your first box plus $20 off. To receive this offer, go to ButcherBox.com/farmacy. BiOptimizers is offering my listeners 10% off Sleep Breakthrough. If you buy two or more, you’ll get a free bottle of Magnesium Breakthrough. This is a limited-time offer. Go to sleepbreakthrough.com/hyman and use the code hyman10. Levels provides real-time feedback on how diet and lifestyle choices impact your metabolic health. Right now, Levels is offering an additional two free months of their annual membership. Learn more at levels.link/HYMAN. Here are more details from our interview (audio version / Apple Subscriber version): Hormone illiteracy and why we need more hormonal education (6:48 / 3:30) Why so many women struggle with hormonal issues (10:32 / 6:55)  Managing hormones with fasting (14:31 / 11:56)  What happens when we fast (18:43 / 16:08)  Different types of fasting (23:45 / 20:20)  Reintroducing food after a fast (28:39 / 24:00)  Who shouldn’t fast (38:22 / 33:27)  Detoxification and fasting (39:35 / 34:39)  When to use hormone therapy (42:53 / 38:00)  Hormonal testing (52:13 / 47:20)  Learn more at drmindypelz.com and get a copy of Fast Like a Girl: A Woman's Guide to Using the Healing Power of Fasting to Burn Fat, Boost Energy, and Balance Hormones. Learn more about your ad choices. Visit megaphone.fm/adchoices