Artificial intelligence has made great strides of late, in areas as diverse as playing Go and recognizing pictures of dogs. We still seem to be a ways away from AI that is “intelligent” in the human sense, but it might not be too long before we have to start thinking seriously about the “motivations” and “purposes” of artificial agents. Stuart Russell is a longtime expert in AI, and he takes extremely seriously the worry that these motivations and purposes may be dramatically at odds with our own. In his book Human Compatible, Russell suggests that the secret is to give up on building our own goals into computers, and rather programming them to figure out our goals by actually observing how humans behave.Support Mindscape on Patreon.Stuart Russell received his Ph.D. in computer science from Stanford University. He is currently a Professor of Computer Science and the Smith-Zadeh Professor in Engineering at the University of California, Berkeley, as well as an Honorary Fellow of Wadham College, Oxford. He is a co-founder of the Center for Human-Compatible Artificial Intelligence at UC Berkeley. He is the author of several books, including (with Peter Norvig) the classic text Artificial Intelligence: A Modern Approach. Among his numerous awards are the IJCAI Computers and Thought Award, the Blaise Pascal Chair in Paris, and the World Technology Award. His new book is Human Compatible: Artificial Intelligence and the Problem of Control.Web pageGoogle Scholar publicationsWikipediaTalk on Provably Beneficial Artificial IntelligenceAmazon author pageSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Human beings have a strange fascination with dangerous, predatory animals — bears, lions, wolves, sharks, and more. The top of the food chain is an interesting and precarious place to live; while you might be the boss of your local environment, you also depend on the functioning of an entire ecology. Rae Wynn-Grant is a carnivore ecologist who studies how large predators migrate, feed, reproduce — and especially how they interact with humans. We talk about the diverse social structures of different species of carnivores, how they find mates, and how they diversify their diet. And of course we discuss how humans and other locally-dominant species can live together peacefully.Rae Wynn-Grant received her Ph.D. in Ecology and Evolution from Columbia University. She is currently a Fellow with National Geographic Society working on carnivore conservation in partnership with the American Prairie Reserve. She maintains a Visiting Scientist position at the American Museum of Natural History, and adjunct faculty positions at Columbia University and Johns Hopkins University. She appears in National Geographic’s Born Wild: The Next Generation, premiering on April 22.Web siteNational Geographic web pageAMNH web pageJohns Hopkins web pageTalk on Humans and Conflicts with BearsTwitterSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

It’s hard doing science when you only have one data point, especially when that data point is subject to an enormous selection bias. That’s the situation faced by people studying the nature and prevalence of life in the universe. The only biosphere we know about is our own, and our knowing anything at all is predicated on its existence, so it’s unclear how much it can teach us about the bigger picture. That’s why it’s so important to search for life elsewhere. Today’s guest is Kevin Hand, a planetary scientist and astrobiologist who knows as much as anyone about the prospects for finding life right in our planetary backyard, on moons and planets in the Solar System. We talk about how life comes to be, and reasons why it might be lurking on Europa, Titan, or elsewhere.Support Mindscape on Patreon.Kevin Hand received his Ph.D. in Geological and Environmental Sciences from Stanford University. He is currently Deputy Chief Scientist for Solar System Exploration at NASA’s Jet Propulsion Laboratory. He has collaborated with director James Cameron, and is a frequent consultant on films, including acting as a science advisor to the movie Europa Report. His a cofounder of Cosmos Education, a non-profit organization devoted to science education in developing countries. His new book is Alien Oceans: The Search for Life in the Depths of Space.JPL web pageGoogle Scholar publicationsTalk on Ocean Worlds of the Outer Solar SystemWikipediaTwitterSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

If one of the ambitious goals of philosophy is to determine the meaning of life, one of the ambitious goals of psychology is to tell us how to achieve it. An influential work in this direction was Abraham Maslow’s hierarchy of needs — a list of human needs, often displayed suggestively in the form of a pyramid, ranging from the most basic (food and shelter) to the most refined. At the top lurks “self-actualization," the ultimate goal of achieving one’s creative capacities. Psychologist Scott Barry Kaufman has elaborated on this model, both by exploring less-well-known writings of Maslow’s, and also by incorporating more recent empirical psychological studies. He suggests the more dynamical metaphor of a sailboat, where the hull represents basic security needs and the sail more creative and dynamical capabilities. It’s an interesting take on the importance of appreciating that the nature of our lives is one of constant flux.Support Mindscape on Patreon.Scott Barry Kaufman received his Ph.D. in cognitive psychology from Yale University. He has taught at Columbia University, NYU, the University of Pennsylvania, and elsewhere. He is the host of The Psychology Podcast. He was named by Business Insider as one of the “50 groundbreaking scientists who are changing the way we see the world.” He is the author of numerous books; his most recent, Transcend: The New Science of Self-Actualization, is published April 7.Web siteThe Psychology PodcastGoogle Scholar publicationsAmazon.com author pageDiscussion on “Defining Intelligence”WikipediaTwitterSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Science costs money. And for a brief, glorious period between the start of the Manhattan Project in 1939 and the cancellation of the Superconducting Super Collider in 1993, physics was awash in it, largely sustained by the Cold War. Things are now different, as physics — and science more broadly — has entered a funding crunch. David Kaiser, who is both a working physicist and an historian of science, talks with me about the fraught relationship between scientists and their funding sources throughout history, from Galileo and his patrons to the current rise of private foundations. It’s an interesting listen for anyone who wonders about the messy reality of how science gets done.Support Mindscape on Patreon.David Kaiser received a Ph.D. in physics, and a separate Ph.D. in history of science, from Harvard University. He is currently Germeshausen Professor of the History of Science in MIT’s Program in Science, Technology, and Society, Professor of Physics in MIT’s Department of Physics, and also Associate Dean for Social and Ethical Responsibilities of Computing (SERC) in MIT’s Schwarzman College of Computing. He has been awarded the Davis Prize and Pfizer Prize from the History of Science Society, was named a Mac Vicar Faculty Fellow for undergraduate teaching at MIT, and received the Perkins Award for excellence in mentoring graduate students. His book Quantum Legacies: Dispatches from an Uncertain World is available April 3.Web pageGoogle Scholar publicationsAmazon author pageWikipediaSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What direction does time point in? None, really, although some people might subconsciously put the past on the left and the future on the right, or the past behind themselves and the future in front, or many other possible orientations. What feels natural to you depends in large degree on the native language you speak, and how it talks about time. This is a clue to a more general phenomenon, how language shapes the way we think. Lera Boroditsky is one of the world’s experts on this phenomenon. She uses how different languages construe time and space (as well as other things) to help tease out the way our brains make sense of the world.Support Mindscape on Patreon.Lera Boroditsky received her Ph.D. in cognitive psychology from Stanford University. She is currently associate professor of cognitive science at UC San Diego. She serves as Editor in Chief of the journal Frontiers in Cultural Psychology. She has been named one of 25 Visionaries changing the world by the Utne Reader, and is also a Searle Scholar, a McDonnell scholar, recipient of an NSF Career award, and an APA Distinguished Scientist lecturer.Web siteUC San Diego web pageGoogle Scholar publicationsWikipediaTalk on How Language Shapes the Way We ThinkTwitterSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

This is a special episode of Mindscape, thrown together quickly. Many thanks to Tara Smith for joining me on short notice. Tara is an epidemiologist, and a great person to talk to about the novel coronavirus (and its associated disease, COVID-19) pandemic currently threatening the world. We talk about what viruses are, how they spread, and a lot of the science behind virology and pandemics. We also take a practical turn, talking about what measures (washing hands, social distancing, self-isolation) are useful at combating the spread of the virus, and which (wearing masks) are probably not. Then we look to the future, to ask what the endgame here is; Tara suggests that the kind of drastic measure we are currently putting up with might last a long time indeed.Tara Smith received her Ph.D. in microbiology from the University of Toledo. She is currently Professor of Epidemiology at the Kent State University College of Public Health. She has researched and written extensively about diseases such as ebola and MRSA. She is an active science communicator, and writes regular columns for SELF magazine.Web siteKent State web pageGoogle Scholar publicationsWikipediaAmazon author pageTwitterSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

“What good is half a wing?” That’s the rhetorical question often asked by people who have trouble accepting Darwin’s theory of evolution by natural selection. Of course it’s a very answerable question, but figuring out what exactly the answer is leads us to some fascinating biology. Neil Shubin should know: he is the co-discoverer of Tiktaalik Roseae, an ancient species of fish that was in the process of learning to walk and breathe on land. We talk about how these major transitions happen — typically when evolution finds a way to re-purpose existing organs into new roles — and how we can learn about them by studying living creatures and the information contained in their genomes.Support Mindscape on Patreon.Neil Shubin received his Ph.D. in organismic and evolutionary biology from Harvard University. He is currently the the Robert Bensley Distinguished Service Professor and Associate Dean of Biological Sciences at the University of Chicago. He is a member of the National Academy of Sciences and the American Philosophical society. His first book, Your Inner Fish, was chosen by the National Academy of Sciences as the best science book of 2009, and was subsequently made into a TV special. His new book is Some Assembly Required: Decoding Four Billion Years of Life, from Ancient Fossils to DNA.Web siteUniversity of Chicago web pageGoogle Scholar publicationsWikipediaAmazon author pageYour Inner Fish on PBSTwitterSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

If you tell me that one of the world’s leading neuroscientists has developed a theory of how the brain works that also has implications for the origin and nature of life more broadly, and uses concepts of entropy and information in a central way — well, you know I’m going to be all over that. So it’s my great pleasure to present this conversation with Karl Friston, who has done exactly that. One of the most highly-cited neuroscientists now living, Friston has proposed that we understand the brain in terms of a free energy principle, according to which our brains are attempting to model the world in such a way as to minimize the amount of surprise we experience. It’s a bit more complicate than that, but I think we made great headway in explicating some very profound ideas in a way that should be generally understandable.Support Mindscape on Patreon.Karl Friston received his medical degree from King’s College Hospital, London. He is currently Professor at the Institute of Neurology, University College London, and Wellcome Principal Research Fellow and Scientific Director of the Wellcome Trust Centre for Neuroimaging. Among his major contributions are statistical parametric mapping, voxel-based morphometry, and dynamical causal modeling. He is a Fellow of the Royal Society, of the Academy of Medical Science, and of the Royal Society of Biology. Among his awards are the Young Investigators Award in Human Brain Mapping, the Minerva Golden Brain Award, the Weldon Memorial Prize, the Charles Branch Award, and the Glass Brain Award for human brain mapping.Web pageGoogle Scholar publicationsTalk on “I Am, Therefore I Think”Article on “The Free-Energy Principle: A Unified Brain Theory?”WikipediaSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Anyone who has read histories of the Cold War, including the Cuban Missile Crisis and the 1983 nuclear false alarm, must be struck by how incredibly close humanity has come to wreaking incredible destruction on itself. Nuclear war was the first technology humans created that was truly capable of causing such harm, but the list of potential threats is growing, from artificial pandemics to runaway super-powerful artificial intelligence. In response, today’s guest Martin Rees and others founded the Cambridge Centre for the Study of Existential Risk. We talk about what the major risks are, and how we can best reason about very tiny probabilities multiplied by truly awful consequences. In the second part of the episode we start talking about what humanity might become, as well as the prospect of life elsewhere in the universe, and that was so much fun that we just kept going.Support Mindscape on Patreon.Lord Martin Rees, Baron of Ludlow, received his Ph.D. in physics from University of Cambridge. He is currently Emeritus Professor of Cosmology and Astrophysics at the University of Cambridge, as well as Astronomer Royal of the United Kingdom. He was formerly Master of Trinity College and President of the Royal Society. Among his many awards are the Heineman Prize for Astrophysics, the Gruber Prize in Cosmology, the Crafoord Prize, the Michael Faraday Prize, the Templeton Prize, the Isaac Newton Medal, the Dirac Medal, and the British Order of Merit. He is a co-founder of the Centre for the Study of Existential Risk.Web pageInstitute for Astronomy, Cambridge, web pageGoogle Scholar publicationsAmazon.com author pageWikipediaCentre for the Study of Existential RiskSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

It’s hard to make decisions that will change your life. It’s even harder to make a decision if you know that the outcome could change who you are. Our preferences are determined by who we are, and they might be quite different after a decision is made — and there’s no rational way of taking that into account. Philosopher L.A. Paul has been investigating these transformative experiences — from getting married, to having a child, to going to graduate school — with an eye to deciding how to live in the face of such choices. Of course we can ask people who have made such a choice what they think, but that doesn’t tell us whether the choice is a good one from the standpoint of our current selves, those who haven’t taken the plunge. We talk about what this philosophical conundrum means for real-world decisions, attitudes towards religious faith, and the tricky issue of what it means to be authentic to yourself when your “self” keeps changing over time.Support Mindscape on Patreon.L.A. (Laurie) Paul received her Ph.D. in philosophy from Princeton University. She is currently professor of philosophy and cognitive science at Yale University. She has worked extensively on causation, the philosophy of time, mereology, and transformative experience. She has won fellowships from the Guggenheim Foundation, the National Humanities Center, and the Australian National University. Among her books are the monograph Transformative Experience; she is currently working on a popular-level book on this theme.Web siteYale web pagePhilPeople profileGoogle Scholar publicationsAmazon.com author pageWikipediaTwitterSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Nations generally want their economies to be rich, robust, and growing. But it’s also important to person to ensure that wealth doesn’t flow only to a few people, but rather that as many people as possible can enjoy the benefits of a healthy economy. As is well known, the best way to balance these interests is a contentious subject. On one side we might find free-market fundamentalists who want to let supply and demand set prices and keep government interference to a minimum, while on the other we might find enthusiasts for very strong government control over all aspects of the economy. Suresh Naidu is an economist who has delved deeply into how economic performance affects and is affected by other notable social factors, from democracy to revolution to slavery. We talk about these, as well as how concentrations of economic power in just a few hands — monopoly and its cousin, monopsony — can distort the best intentions of the free market.Support Mindscape on Patreon.Suresh Naidu received his Ph.D. in economics from the University of California, Berkeley. He is currently professor of economics and international affairs at Columbia University as well as a fellow at Roosevelt Institute, external faculty at the Santa Fe Institute, and a research fellow at National Bureau of Economic Research. His awards include a Sloan Research Fellowship and the “Best Ph.D. Advisor Award” from the Columbia Association of Graduate Economics Students.Columbia School of International and Public Affairs pageSanta Fe Institute pageEquitable Growth pageGoogle Scholar publicationsThe Economy online textbookTwitterSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

The Greek statesman Demosthenes is credited with saying “I am a citizen of the world,” and the idea that we should take a cosmopolitan view of our common humanity is a compelling one. Not everyone agrees, however; in the words of former British Prime Minister Theresa May, “If you are a citizen of the world, you are a citizen of nowhere.” On the other side of the political spectrum, groups who share a feature of identity — race, ethnicity, gender, sexuality, and others — find it useful to band together to make political progress. Kwame Anthony Appiah is a leading philosopher and cultural theorist who has thought carefully about the tricky issues of cosmopolitanism and identity. We talk about how identities form, why they matter, and how to negotiate the difficult balance between being human and being your particular self.Support Mindscape on Patreon.Kwame Anthony Appiah received his Ph.D. in philosophy from Cambridge University. He is currently Professor of Philosophy and of Law at New York University. He is the author of numerous academic books as well as several novels. He is a fellow of the American Academy of Arts and Sciences, and is the recipient of a number of major awards, including the National Humanities Medal of the United States. He currently writes the New York Times Magazine column “The Ethicist“, and frequently writes for The New York Review of Books. (Note that in the podcast intro I mistakenly said he was “born and raised” in Ghana; he was actually born in London, moving to Ghana when he was six months old.)Web siteNYU web pageGoogle Scholar publicationsAmazon.com author pageTalk on “Beyond Identity”WikipediaTwitterSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

The Convention on Psychotropic Substances was a 1971 United Nations treaty that placed strong restrictions on the use of psychedelic drugs — not only on personal use, but medical and scientific research as well. Along with restrictions placed by individual nations, it has been very difficult for scientists to study the effects of psychedelics on the brain, despite indications that they might have significant therapeutic potential. But this has gradually been changing, and researchers like Robin Carhart-Harris have begun to perform controlled experiments to see how psychedelics affect the brain, and what positive uses they might have. Robin and I talk about how psychedelics work, how they can help with conditions from addiction to depression, and how they can help people discover things about themselves.Support Mindscape on Patreon.Robin Carhart-Harris received his Ph.D. in psychopharmacology from the University of Bristol. He is currently the Director of the Centre for Psychedelic Research in the Department of Brain Sciences at Imperial College London, and holds an honorary position at the University of Oxford. His research involves functional brain imaging studies with psilocybin (magic mushrooms), LSD, MDMA (ecstasy) and DMT (ayahuasca), plus a clinical trial of psilocybin for treatment-resistant depression.Web siteCentre for Psychedelic ResearchGoogle Scholar pageTalk on Psychedelics: Lifting the VeilTwitterSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

People have always disagreed about politics, passionately and sometimes even violently. But in certain historical moments these disagreements were distributed without strong correlations, so that any one political party would contain a variety of views. In a representative democracy, that kind of distribution makes it easier to accomplish things. In contrast, today we see strong political polarization: members of any one party tend to line up with each other on a range of issues, and correspondingly view the other party with deep distrust. Political commentator Ezra Klein has seen this shift in action, and has studied it carefully in his new book Why We’re Polarized. We talk about the extent to which the apparent polarization is real, how we can trace its causes, and whether there’s anything we can do about it.Support Mindscape on Patreon.Ezra Klein received a B.A. in political science from the University of California, Los Angeles. He is currently the editor-at-large and founder of Vox. As a writer and editor his work has appeared in/on The Washington Post, MSNBC, Bloomberg, The New York Review of Books, and The New Yorker. Among his awards are Blogger of the Year (The Week), 50 Most Powerful People in Washington DC (GQ), Best Online Commentary (Online News Association), and the Carey McWilliams Award (American Political Science Association).Vox profileThe Ezra Klein Show podcastWhy We’re PolarizedWikipediaTwitterSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Physics is simple; people are complicated. But even people are ultimately physical systems, made of particles and forces that follow the rules of the Core Theory. How do we bridge the gap from one kind of description to another, explaining how someone we know and care about can also be “just” a set of quantum fields obeying impersonal laws? This is a hard question that comes up in a variety of forms — What is the “self”? Do we have free will, the ability to make choices? What are the moral and ethical ramifications of these considerations? Jenann Ismael is a philosopher at the leading edge of connecting human life to the fundamental laws of nature, for example in her recent book How Physics Makes Us Free. We talk about free will, consciousness, values, and other topics about which I’m sure everyone will simply agree.Support Mindscape on Patreon.Jenann Ismael received her Ph.D. in philosophy from Princeton University. She is currently Professor of Philosophy at Columbia University. Her work includes both the foundations of physics (spacetime, quantum mechanics, symmetry) and the philosophy of mind and cognition. She has been awarded fellowships from Stanford University, the Australian Research Council, the Scots Philosophical Association, and the Center for Advanced Study in Social and Behavioral Sciences, as well as an Essay Prize from the British Society for the Philosophy of Science.Web siteColumbia web pagePhilPeople profileAmazon author pageCloser to Truth interviewWikipedia“Well-Being and Time,” David Velleman (mentioned in the episode)See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

We are all alive, but “life” is something we struggle to understand. How do we distinguish a “living organism” from an emergent dynamical system like a hurricane, or a resource-consuming chemical reaction like a forest fire, or an information-processing system like a laptop computer? There is probably no one crisp set of criteria that delineates life from non-life, but it’s worth the exercise to think about what we really mean, especially as the quest to find life outside the confines of the Earth picks up steam. Sara Imari Walker planned to become a cosmologist before shifting her focus to astrobiology, and is now a leading researcher on the origin and nature of life. We talk about what life is and how to find it, with a special focus on the role played by information and computation in living beings.Support Mindscape on Patreon.Sara Imari Walker received her Ph.D. in physics from Dartmouth college. She is currently Associate Professor in the School of Earth and Space Exploration at Arizona State University, Deputy Director of the Beyond Center for Fundamental Concepts in Science, and Associate Director of the ASU-Santa Fe Institute Center for Biosocial Complex Systems. She is the co-founder of the astrobiology social network SAGANet, and serves on the Board of Directors for Blue Marble Space.Web siteGoogle Scholar pageAsk an Astrobiologist interviewTalk on A Theory of LifeWikipediaTwitterSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Wilfrid Sellars described the task of philosophy as explaining how things, in the broadest sense of term, hang together, in the broadest sense of the term. (Substitute “exploring” for “explaining” and you’d have a good mission statement for the Mindscape podcast.) Few modern thinkers have pursued this goal more energetically, creatively, and entertainingly than Daniel Dennett. One of the most respected philosophers of our time, Dennett’s work has ranged over topics such as consciousness, artificial intelligence, metaphysics, free will, evolutionary biology, epistemology, and naturalism, always with an eye on our best scientific understanding of the phenomenon in question. His thinking in these areas is exceptionally lucid, and he has the rare ability to express his ideas in ways that non-specialists can find accessible and compelling. We talked about all of them, in a wide-ranging and wonderfully enjoyable conversation.Support Mindscape on Patreon.Daniel Dennett received his D.Phil. in philosophy from Oxford University. He is currently Austin B. Fletcher Professor of Philosophy and co-director of the Center for Cognitive Studies at Tufts University. He is known for a number of philosophical concepts and coinages, including the intentional stance, the Cartesian theater, and the multiple-drafts model of consciousness. Among his honors are the Erasmus Prize, a Guggenheim Fellowship, and the American Humanist Association’s Humanist of the Year award. He is the author of a number of books that are simultaneously scholarly and popular, including Consciousness Explained, Darwin’s Dangerous Idea, and most recently Bacteria to Bach and Back.Web siteBibliographyGoogle Scholar pageAmazon author pageWikipediaTalk on The Illusion of ConsciousnessCenter for Cognitive StudiesThe Clergy ProjectTwitterSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Welcome to the second annual Mindscape Holiday Message! No substantive content or deep ideas, just me talking a bit about the state of the podcast and what’s on my mind. Since the big event for me in 2019 was the publication of Something Deeply Hidden, I thought it would be fun to talk about the process of writing and selling a popular book. Might be of interest to some of you out there!Mindscape takes off for the holidays, so the next regular episode will be published on Monday January 6. It’s a good one — maybe my favorite episode thus far.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In the United States, more than one in five deaths is caused by cancer. The medical community has put enormous resources into fighting this disease, yet its causes and best treatments continue to be a puzzle. Azra Raza has been on both sides of the patient’s bed, as she puts it — both as an oncologist and expert in the treatment of Myelodisplastic Syndrome (MDS), and as a wife who lost her husband to cancer. In her new book, The First Cell, she argues that we have placed too much emphasis on treating cancer once it has already developed, and not nearly enough on catching it as soon as possible. We talk about what cancer is and why it’s such a difficult disease to understand, as well as discussing how patients and their loved ones should face up to the challenges of dealing with cancer.Support Mindscape on Patreon.Azra Raza received her M.D. from Dow Medical College in Karachi, Pakistan. She is currently Chan Soon-Shiong Professor of Medicine and Director of the MDS Center at Columbia University in New York. Previously she was the Chief of Hematology-Oncology and the Gladys Smith Martin Professor of Oncology at the University of Massachusetts. Her Tissue Repository contains over 60,000 samples of samples from MDS and acute leukemia patients. She is the co-editor of the celebrated blog site 3 Quarks Daily.Web siteColumbia University Medical Center pageFirst Cell CenterWikipediaThe First CellConversation With Siddhartha MukherjeeTwitterSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

It’s too easy to take laws of nature for granted. Sure, gravity is pulling us toward Earth today; but how do we know it won’t be pushing us away tomorrow? We extrapolate from past experience to future expectation, but what allows us to do that? “Humeans” (after David Hume, not a misspelling of “human”) think that what exists is just what actually happens in the universe, and the laws are simply convenient summaries of what happens. “Anti-Humeans” think that the laws have an existence of their own, bringing what happens next into existence. The debate has implications for the notion of possible worlds, and thus for counterfactuals and causation — would Y have happened if X hadn’t happened first? Ned Hall and I have a deep conversation that started out being about causation, but we quickly realized we had to get a bunch of interesting ideas on the table first. What we talk about helps clarify how we should think about our reality and others.Support Mindscape on Patreon.Edward (Ned) Hall received his Ph.D. in philosophy from Princeton University. He is currently Department Chair and Norman E. Vuilleumier Professor of Philosophy at Harvard University. According to his web page, “I work on a range of topics in metaphysics and epistemology that overlap with philosophy of science. (Which is to say: the best topics in metaphysics and epistemology.)” He is the coauthor (with L.A. Paul) of Causation: A User’s Guide.Web sitePhilPeople profileWikipediaDialogue on causation with Laurie PaulSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

We've talked a lot recently about the Many Worlds of quantum mechanics. That’s one kind of multiverse that physicists often contemplate. There is also the cosmological multiverse, which we talked about with Brian Greene. Today’s guest, Max Tegmark, has thought a great deal about both of those ideas, as well as a more ambitious and speculative one: the Mathematical Multiverse, in which we imagine that every mathematical structure is real, and the universe we perceive is just one such mathematical structure. And there’s yet another possibility, that what we experience as “reality” is just a simulation inside computers operated by some advanced civilization. Max has thought about all of these possibilities at a deep level, as his research has ranged from physical cosmology to foundations of quantum mechanics and now to applied artificial intelligence. Strap in and be ready for a wild ride.Max Tegmark received his Ph.D. in physics from the University of California, Berkeley. He is currently professor of physics at the Massachusetts Institute of Technology. He has played an important role analyzing data from large-scale structure and the cosmic microwave background. He is the author of Our Mathematical Universe and Life 2.0: Being Human in the Age of Artificial Intelligence. He is a co-founder of the Foundational Questions Institute and the Future of Life Institute.Web siteGoogle Scholar pageWikipediaAmazon author pageTalk on AITwitterSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

An infinite number of things happen; we bring structure and meaning to the world by making art and telling stories about it. Every work of literature created by human beings comes out of an historical and cultural context, and drawing connections between art and its context can be illuminating for both. Today’s guest, Stephen Greenblatt, is one of the world’s most celebrated literary scholars, famous for helping to establish the New Historicism school of criticism, which he also refers to as “cultural poetics.” We talk about how art becomes entangled with the politics of its day, and how we can learn about ourselves and other cultures by engaging with stories and their milieu.Support Mindscape on Patreon.Stephen Greenblatt received his Ph.D. in English from Yale University. He is currently Cogan University Professor of the Humanities at Harvard University. He has specialized in Renaissance and Shakespeare studies, but has also written on topics as diverse as Adam and Eve and the ancient Roman poet Lucretius. He has served as the editor of the Norton Anthology of English Literature and the Norton Shakespeare, and is founder of the journal Representations. Among his many honors are the Pulitzer Prize, the National Book Award, and the Distinguished Humanist Award from the Mellon Foundation. His most recent book is Tyrant: Shakespeare on Politics.Web siteHarvard web pageWikipediaAmazon.com author pageOnline courses at edXTalk on Will in the World: How Shakespeare Became ShakespeareSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Changing technologies have always affected how we produce and enjoy art, and music might be the most obvious example. Radio and recordings made it easy for professional music to be widely disseminated, but created a barrier to its creation. Nowadays computers are helping to reverse that trend, allowing casual users to create slick songs of their own. Not everyone is equally good at it, however; Grimes (who currently goes by c, the symbol for the speed of light) is a wildly successful electronic artist who writes, produces, performs, and sings her own songs. We dig into how music is made in the modern world, but also go well beyond that, into artificial intelligence and the nature of digital/virtual/online personae. We talk about the birth of a new digital avatar -- who might be called "War Nymph"? -- and how to navigate the boundaries of art, technology, fashion, and culture. Her new album Miss Anthropocene will be released in February 2020.Support Mindscape on Patreon.Grimes, or c, studied neuroscience at McGill University before turning full-time to music. Her previous albums include Geidi Primes, Halfaxa, Visions, and Art Angels. Her latest album, Miss Anthropocene, channels the goddess of climate change. On December 5th in Miami, she will be orchestrating the one-night-only rave Bio-Haque.Web siteAllMusic profileWikipediaTwitterInstagramYouTubeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Maxwell's Demon is a famous thought experiment in which a mischievous imp uses knowledge of the velocities of gas molecules in a box to decrease the entropy of the gas, which could then be used to do useful work such as pushing a piston. This is a classic example of converting information (what the gas molecules are doing) into work. But of course that kind of phenomenon is much more widespread -- it happens any time a company or organization hires someone in order to take advantage of their know-how. César Hidalgo has become an expert in this relationship between information and work, both at the level of physics and how it bubbles up into economies and societies. Looking at the world through the lens of information brings new insights into how we learn things, how economies are structured, and how novel uses of data will transform how we live.Support Mindscape on Patreon.César Hidalgo received his Ph.D. in physics from the University of Notre Dame. He currently holds an ANITI Chair at the University of Toulouse, an Honorary Professorship at the University of Manchester, and a Visiting Professorship at Harvard’s School of Engineering and Applied Sciences. From 2010 to 2019, he led MIT’s Collective Learning group. He is the author of Why Information Grows and co-author of The Atlas of Economic Complexity. He is a co-founder of Datawheel, a data visualization company whose products include the Observatory of Economic Complexity.Web siteMIT web pageGoogle Scholar pageWikipediaTalk on replacing politiciansIn My Shoes (documentary film)DatawheelAmazon author pageTwitterSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

The human brain contains roughly 85 billion neurons, wired together in an extraordinarily complex network of interconnected parts. It’s hardly surprising that we don’t understand the mind and how it works. But do we know enough about our experience of consciousness to suggest that consciousness cannot arise from nothing more than the physical interactions of bits of matter? Panpsychism is the idea that consciousness, or at least some mental aspect, is pervasive in the world, in atoms and rocks as well as in living creatures. Philosopher Philip Goff is one of the foremost modern advocates of this idea. We have a friendly and productive conversation, notwithstanding my own view that the laws of physics don’t need any augmenting to ultimately account for consciousness. If you’re not sympathetic toward panpsychism, this episode will at least help you understand why someone might be.Support Mindscape on Patreon.Philip Goff received his Ph.D. in philosophy from the University of Reading. He is currently Assistant Professor in the Department of Philosophy at the University of Durham. His new book, Galileo’s Error: Foundations for a New Science of Consciousness, is being published on Nov. 5.Web siteDurham web pagePhilPeople profileAmazon.com author pageBlogTalk on Consciousness and Fundamental RealityPanpsychism at the Stanford Encyclopedia of PhilosophyTwitterSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Cosmologists are always talking excitedly about the Big Bang and all the cool stuff that happened in the 14 billion years between then and now. But what about the future? We don't know for sure, but we know enough about the laws of physics to sketch out several plausible scenarios for what the future of our universe will hold. Katie Mack is a cosmologist who is writing a book about the end of the universe. We talk about the possibilities of a Big Crunch (and potential Big Bounce), a gentle cooling off where the universe gradually grows silent, and of course the prospect of a dramatic phase transition, otherwise known as the "bubble of quantum death." Which would make a great name for a band, I think we can all agree.Support Mindscape on Patreon.Katherine (Katie) Mack received her Ph.D. in physics from Princeton University. She is currently an Assistant Professor at North Carolina State University, where her research centers on theoretical cosmology, including dark matter and black holes. She is also a member of NCSU’s Leadership in Public Science Cluster. Her upcoming book, The End of Everything, will be published in 2020.Web siteNCSU web pageWikipediaGoogle Scholar publicationsTalk on Death of a UniverseTwitterSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Like so many technological innovations, the internet is something that burst on the scene and pervaded human life well before we had time to sit down and think through how something like that should work and how it should be organized. In multiple ways — as a blogger, activist, fiction writer, and more — Cory Doctorow has been thinking about how the internet is affecting our lives since the very beginning. He has been especially interested in legal issues surrounding copyright, publishing, and free speech, and recently his attention has turned to broader economic concerns. We talk about how the internet has become largely organized through just a small number of quasi-monopolistic portals, how this affects the ways in which we gather information and decide whether to trust outside sources, and where things might go from here.Cory Doctorow is a science fiction writer, activist, journalist, and blogger. He is a co-editor of the website Boing Boing, and works as a special consultant for the Electronic Frontier Foundation. He is the author of the nonfiction book Information Doesn’t Want to Be Free as well as science-fiction works such as Walkaway and Radicalized. He has been awarded an honorary doctorate from the Open University, where he is also a Visiting Professor, as well as being an MIT Media Lab Research Affiliate and a Visiting Professor of Practice at the University of South Carolina’s School of Library and Information Science.Web siteBoing BoingPodcastWikipediaAmazon.com author pageTwitterElectronic Frontier FoundationSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Artificial intelligence is better than humans at playing chess or go, but still has trouble holding a conversation or driving a car. A simple way to think about the discrepancy is through the lens of “common sense” — there are features of the world, from the fact that tables are solid to the prediction that a tree won’t walk across the street, that humans take for granted but that machines have difficulty learning. Melanie Mitchell is a computer scientist and complexity researcher who has written a new book about the prospects of modern AI. We talk about deep learning and other AI strategies, why they currently fall short at equipping computers with a functional “folk physics” understanding of the world, and how we might move forward.Support Mindscape on Patreon.Melanie Mitchell received her Ph.D. in computer science from the University of Michigan. She is currently a professor of computer science at Portland State University and an external professor at the Santa Fe Institute. Her research focuses on genetic algorithms, cellular automata, and analogical reasoning. She is the author of An Introduction to Genetic Algorithms, Complexity: A Guided Tour, and most recently Artificial Intelligence: A Guide for Thinking Humans. She originated the Santa Fe Institute’s Complexity Explorer project, on online learning resource for complex systems.Web siteSanta Fe web pageWikipediaGoogle ScholarComplexity ExplorerAmazon.com author pageTwitterSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Our observable universe started out in a highly non-generic state, one of very low entropy, and disorderliness has been growing ever since. How, then, can we account for the appearance of complex systems such as organisms and biospheres? The answer is that very low-entropy states typically appear simple, and high-entropy states also appear simple, and complexity can emerge along the road in between. Today’s podcast is more of a discussion than an interview, in which behavioral neuroscientist Kate Jeffery and I discuss how complexity emerges through cosmological and biological evolution. As someone on the biological side of things, Kate is especially interested in how complexity can build up and then catastrophically disappear, as in mass extinction events.There were some audio-quality issues with the remote recording of this episode, but loyal listeners David Gennaro and Ben Cordell were able to help repair it. I think it sounds pretty good!Support Mindscape on Patreon.Kate Jeffery received her Ph.D. in behavioural neuroscience from the University of Edinburgh. She is currently a professor in the Department of Behavioural Neuroscience at University College, London. She is the founder and Director of the Institute of Behavioural Neuroscience at UCL.Lab web siteInstitute of Behavioural NeuroscienceResearchGate pageTalk on Cognitive Neuroscience and ArchitectureTwitterSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

The idea of “red states” and “blue states” burst on the scene during the 2000 U.S. Presidential elections, and has a been a staple of political commentary ever since. But it’s become increasingly clear, and increasingly the case, that the real division isn’t between different sets of states, but between densely- and sparsely-populated areas. Cities are blue (liberal), suburbs and the countryside are red (conservative). Why did that happen? How does it depend on demographics, economics, and the personality types of individuals? I talk with policy analyst Will Wilkinson about where this division came from, and what it means for the future of the country and the world.Support Mindscape on Patreon.Will Wilkinson received an M.A. in philosophy from Northern Illinois University, and an MFA in creative writing from the University of Houston. He has worked for the Mercatus Center at George Mason University and as a research fellow at the Cato Institute, and is currently Vice President of Policy at the Niskanen Center. He has taught at Howard University, the University of Maryland, the University of Tennessee at Chattanooga, and the Iowa Writers’ Workshop. He has written for a wide variety of publications, including The New York Times, The Economist, The Washington Post, The Atlantic, Vox, and The Boston Review, as well as being a regular commentator for Marketplace on public radio.Web siteNiskanen web pageThe Density Divide: Urbanization, Polarization, and Populist BacklashWriting at The New York TimesWikipediaTwitterSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

We had our fun last week, exploring how progress in renewable energy and electric vehicles may help us combat encroaching climate change. This week we’re being a bit more hard-nosed, taking a look at what’s currently happening to our climate. Michael Mann is one of the world’s leading climate scientists, and also a dedicated advocate for improved public understanding of the issues. It was his research with Raymond Bradley and Malcolm Hughes that introduced the “hockey stick” graph, showing how global temperatures have increased rapidly compared to historical averages. We dig a bit into the physics behind the greenhouse effect, the methods that are used to reconstruct temperatures in the past, how the climate has consistently been heating up faster than the average models would have predicted, and the relationship between climate change and extreme weather events. Happily even this conversation is not completely pessimistic — if we take sufficiently strong action now, there’s still time to avert the worst possible future catastrophe.Support Mindscape on Patreon.Michael Mann received his Ph.D. in Geology and Geophysics from Yale University. He is currently Distinguished Professor of Atmospheric Science at Pennsylvania State University, with joint appointments in the Departments of Geosciences and the Earth and Environmental Systems Institute. He is the director of Penn State’s Earth System Science Center. He is the author of over 200 scientific publications and four books. His most recent book is The Tantrum that Saved the World, a “carbon-neutral kids’ book.”Web sitePenn State web pageEarth System Science CenterGoogle scholarAmazon.com author pageWikipediaTwitterSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

The Earth is heating up, and it’s our fault. But human beings are not always complete idiots (occasional contrary evidence notwithstanding), and sometimes we can even be downright clever. Dare we imagine that we can bring our self-inflicted climate catastrophe under control, through a combination of technological advances and political willpower? Ramez Naam is optimistic, at least about the technological advances. He is a technologist, entrepreneur, and science-fiction author, who has been following advances in renewable energy. We talk about the present state of solar, wind, and other renewable energy sources, and what our current rate of progress bodes for the near and farther future. And maybe we sneak in a little discussion of brain-computer interfaces, a theme of the Nexus trilogy.Support Mindscape on Patreon.Ramez Naam worked for 13 years at Microsoft, helping to develop early versions of Outlook, Explorer, and Bing. He founded Apex Technologies, which develops software for use in molecular design. He holds 19 patents. His science-fiction trilogy Nexus was awarded several prizes. He is chair of Energy and Environmental Systems at Singularity University.Web siteSingularity University pageAmazon.com author pageWikipediaTalk on Exponential EnergyTwitterSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

I suspect most loyal Mindscape listeners have been exposed to the fact that I’ve written a new book, Something Deeply Hidden: Quantum Worlds and the Emergence of Spacetime. As I release this episode on Monday 9 September 2019, the book will officially be released tomorrow, in print, e-book, and audio versions. To get in the mood, we’ve had several podcast episodes on quantum mechanics, but the “emergence of spacetime” aspect has been neglected. So today we have a solo podcast in which I explain a bit about the challenges of quantum gravity, how Many-Worlds provides the best framework for thinking about quantum gravity, and how entanglement could be the key to showing how a curved spacetime could emerge from a quantum wave function. All of this stuff is extremely speculative, but I’m excited about the central theme that we shouldn’t be trying to “quantize gravity,” but instead looking for gravity within quantum mechanics. The ideas here go pretty far, but hopefully they should be accessible to everyone.Support Mindscape on Patreon.The end of this episode includes a bonus, a short snippet from the audio book, read by yours truly. Audio excerpted courtesy Penguin Random House Audio. And here are links to some of the technical papers mentioned in the podcast.Something Deeply Hidden: Quantum Worlds and the Emergence of Spacetime“Thermodynamics of Space-Time: The Einstein Equation of State” (Jacobson)“Space from Hilbert Space: Recovering Geometry from Bulk Entanglement” (Cao, Carroll, and Michalakis)“Bulk Entanglement Gravity without a Boundary: Towards Finding Einstein’s Equation in Hilbert Space” (Cao and Carroll)“Mad-Dog Everettianism: Quantum Mechanics at Its Most Minimal” (Carroll and Singh)See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Physicists study systems that are sufficiently simple that it’s possible to find deep unifying principles applicable to all situations. In psychology or sociology that’s a lot harder. But as I say at the end of this episode, Mindscape is a safe space for grand theories of everything. Psychologist Michele Gelfand claims that there’s a single dimension that captures a lot about how cultures differ: a spectrum between “tight” and “loose,” referring to the extent to which social norms are automatically respected. Oregon is loose; Alabama is tight. Italy is loose; Singapore is tight. It’s a provocative thesis, back up by copious amounts of data, that could shed light on human behavior not only in different parts of the world, but in different settings at work or at school.Support Mindscape on Patreon.Michele Gelfand received her Ph.D. in social psychology from the University of Illinois. She is currently Distinguished University Professor of Psychology and affiliate of the RH Smith School of Business at the University of Maryland, College Park. She is a past president of the International Association for Conflict Management. Among her numerous awards are the Carol and Ed Diener Award in Social Psychology, the Annaliese Research Award from the Alexander von Humboldt Foundation, and the Outstanding International Psychologist Award from the American Psychological Association.Web siteUniversity of Maryland web pageGoogle ScholarWikipediaTEDx talk on the secret life of social normsRule Makers, Rule BreakersTwitterSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

All of us have been wrong about things from time to time. But sometimes it was a simple, forgivable mistake, while other times we really should have been correct. Properties that systematically prevent us from being correct, and for which we can legitimately be blamed, are “intellectual vices.” Examples might include closed-mindedness, wishful thinking, overconfidence, selective attention, and so on. Quassim Cassam is a philosopher who studies knowledge in various forms, and who has recently written a book Vices of the Mind: From the Intellectual to the Political. We talk about the nature of intellectual vices, how they manifest in people and in organizations, and what we can possibly do to correct them in ourselves.Support Mindscape on Patreon.Quassim Cassam received his Ph.D. in philosophy from Oxford University. He is currently Professor of Philosophy at the University of Warwick. He previously held faculty positions at Cambridge University and University College London. He has served as the president of the Aristotelian Society, and was awarded a Leadership Fellowship by the Arts and Humanities Research Council in the UK.Web pagePhilPeople profileWikipediaAmazon.com author pageSelf-Knowlege for Humans web siteTwitterSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Memory takes different forms. Memories can be encoded in the strength of neural connections in our brains, but there’s a sense in which photographs and written records are memories as well. What did people do before such forms of memory even existed? Lynne Kelly is a science writer and researcher who specializes in forms of memory in the ancient world, as well as a competitive memory expert in her own right. She has theorized that ancient structures such as Stonehenge might have served as memory palaces, encoding social knowledge over extended periods of time. We talk about how to improve your own memory, the origin of religion, and how prehistoric cultures preserved their know-how.Support Mindscape on Patreon.Lynne Kelly received her Ph.D. in English from La Trobe University. Originally trained as a computer scientist, she has worked as an educator before transitioning into science writing and memory research. She is an Honorary Research Associate at La Trobe University. She is the author of a number of books, including The Skeptic’s Guide to the Paranormal. Her work on memory methods and ancient societies was published as an academic book, Knowledge and Power in Prehistoric Societies: Orality, Memory, and the Transmission of Culture, as well as in trade form as The Memory Code: The Traditional Aboriginal Memory Technique That Unlocks the Secrets of Stonehenge, Easter Island and Ancient Monuments the World Over. Her most recent book is Memory Craft: Improve Your Memory Using the Most Powerful Methods From Around the World.Web siteTEDx talk on Modern Memory, Ancient MethodsWikipediaAmazon.com author pageTwitterSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

There are many mysteries surrounding quantum mechanics. To me, the biggest mysteries are why physicists haven’t yet agreed on a complete understanding of the theory, and even more why they mostly seem content not to try. This puzzling attitude has historical roots that go back to the Bohr-Einstein debates. Adam Becker, in his book What Is Real?, looks at this history, and discusses how physicists have shied away from the foundations of quantum mechanics in the subsequent years. We discuss why this has been the case, and talk about some of the stubborn iconoclasts who insisted on thinking about it anyway.Support Mindscape on Patreon.Adam Becker received his Ph.D. in physics from the University of Michigan. He is currently a science writer and a Visiting Scholar at the Center for Science, Technology, Medicine & Society at UC Berkeley. His book What Is Real? The Unfinished Quest for the Meaning of Quantum Physics comes out in paperback on Sept. 3, 2019.Web siteBerkeley web pageWhat Is Real?Talk on the history of quantum mechanicsInteractive explanation of Bell’s TheoremWikipediaTwitterSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Fiction shines a light on the human condition by putting people into imaginary situations and envisioning what might happen. Science fiction expands this technique by considering situations in the future, with advanced technology, or with utterly different social contexts. Seth MacFarlane’s show The Orville is good old-fashioned space opera, but it’s also a laboratory for exploring the intricacies of human behavior. There are interpersonal conflicts, sexual politics, alien perspectives, and grappling with the implications of technology. I talk with Seth about all these issues, and maybe a little bit about whether it’s a good idea to block people on Twitter.Support Mindscape on Patreon.Seth MacFarlane is a screenwriter, director, actor, producer, and singer. He is the creator of the animated TV shows Family Guy, American Dad!, and The Cleveland Show. He wrote, directed, and starred in the films Ted, Ted 2, and A Million Ways to Die in the West. He created and stars in the live-action episodic TV show The Orville (which will be moving from Fox to Hulu for its third season). He has recorded several albums as a jazz singer, and was the host of the Academy Awards in 2013. He is an executive producer for the reboot of Cosmos. His honors include several Primetime Emmy Awards, an Annie Award, a Webby Award, a Saturn Award, and a star on the Hollywood Walk of Fame.IMDB profileWikipediaFacebookAllmusic profileThe Orville: IMDB, Wikipedia, YouTubeTwitterSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

“Democracy may not exist, but we’ll miss it when it’s gone” — or so suggests the title of Astra Taylor’s new book. We all know how democracy falls short, in practice, of its lofty ideals; but we can also appreciate how democratic values are crucial in the fight for a more just society. In this conversation, we dig into the nature of democracy, from its origins to the present day. We talk about who gets to participate, how economic inequality affects political inequality, and how democratic ideals manifest themselves in any number of real-world situations.Support Mindscape on Patreon or Paypal.Astra Taylor is a filmmaker, author, and activist. Her documentary films include Zizek!, The Examined Life, and most recently What Is Democracy? Her books include The People’s Platform: Taking Back Power and Culture in the Digital age and the new Democracy May Not Exist, But We’ll Miss It When It’s Gone. She has taught sociology at the university level, and written for publications from n+1 to The London Review of Books. She was active in the Occupy movement, and is a co-founder of the Debt Collective.WikipediaIMDB profileAmazon author pageTrailer for What Is Democracy?Debt CollectiveTwitterSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Scientists can’t quite agree on how to define “life,” but that hasn’t stopped them from studying it, looking for it elsewhere, or even trying to create it. Kate Adamala is one of a number of scientists engaged in the ambitious project of trying to create living cells, or something approximating them, starting from entirely non-living ingredients. Impressive progress has already been made. Designing cells from scratch will have obvious uses is biology and medicine, but also allow us to build biological robots and computers, as well as helping us understand how life could have arisen in the first place, and what it might look like on other planets.Support Mindscape on Patreon or Paypal.Katarzyna (Kate) Adamala received her Ph.D. working with Pier Luigi Luisi at the University of Rome and Jack Szostak at Harvard. She is currently an assistant professor of Genetics, Cell Biology, and Development at the University of Minnesota. She is a member of the Build-A-Cell international collaboration, which brings together multiple groups to work on constructing artificial life.University of Minnesota web pageLab web siteGoogle scholar publicationsTalk on synthetic lifeTwitterBuild-A-CellSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

As you may have heard, I have a new book coming out in September, Something Deeply Hidden: Quantum Worlds and the Emergence of Spacetime. To celebrate, we're going to have more than the usual number of podcasts about quantum mechanics over the next couple of months. Today is an experimental flipped podcast, in which I'm being interviewed by Rob Reid. Rob is the host of the After On podcast, of which this is also an episode. We talk about quantum mechanics generally and my favorite Many-Worlds approach in particular, homing in on the motivation for believing in all those worlds and the potential puzzles that this perspective raises.Support Mindscape on Patreon.Rob Reid received his MBA from Harvard. He currently works as an author, entrepreneur, and podcaster. He was the founder of Listen.com, which was acquired in 2003 by RealNetworks. He has written nonfiction books about Harvard Business School and about the early days of the Web, as well as two novels. His most recent book is the science-fiction novel After On, which is also the name of his podcast.Web siteWikipediaAmazon author pageAfter On podcastTED talk on synthetic biologyTwitterSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

It doesn’t mean much to say music affects your brain — everything that happens to you affects your brain. But music affects your brain in certain specific ways, from changing our mood to helping us learn. As both a neuroscientist and an opera singer, Indre Viskontas is the ideal person to talk about the relationship between music and the brain. Her new book, How Music Can Make You Better, digs into why we love music, how it can unite and divide us, and how music has a special impact on the very young and the very old.   Support Mindscape on Patreon or Paypal. Indre Viskontas received her Ph.D. in Cognitive Neuroscience at UCLA. She is currently a Professor of Sciences and Humanities at the San Francisco Conservatory of Music, and an Adjunct Professor of Psychology at the University of San Francisco. She is also Creative Director of the Pasadena Opera, Director of Vocallective, and host of the Inquiring Minds and Cadence podcasts. She served as the co-host for the documentary series Miracle Detectives, and has produced lecture series for The Great Courses. Her opera performances include roles in Mozart, Puccini, and others. Web site UCSF web page Wikipedia How Music Can Make You Better Great Courses professor page TEDx talk Twitter See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What does it mean to be a good person? To act ethically and morally in the world? In the old days we might appeal to the instructions we get from God, but a modern naturalist has to look elsewhere. Today I do a rare solo podcast, where I talk both about my personal views on morality, a variety of “constructivism” according to which human beings construct their ethical stances starting from basic impulses, logical reasoning, and communicating with others. In light of this view, I consider two real-world examples of contemporary moral controversies: Is it morally permissible to eat meat? Or is there an ethical imperative to be a vegetarian? Do inequities in society stem from discrimination, or from the natural order of things? As a jumping-off point I take the loose-knit group known as the Intellectual Dark Web, which includes Jordan Peterson, Sam Harris, Ben Shapiro, and others, and their nemeses the Social Justice Warriors (though the discussion is about broader issues, not just that group of folks). Probably everyone will agree with my takes on these issues once they listen to my eminently reasonable arguments. Actually this is a more conversational, exploratory episode, rather than a polished, tightly-argued case from start to finish. I don’t claim to have all the final answers. The hope is to get people thinking and conversing, not to settle things once and for all. These issues are, on the one hand, very tricky, and none of us should be too certain that we have everything figured out; on the other hand, they can get very personal, and consequently emotions run high. The issues are important enough that we have to talk about them, and we can at least aspire to do so in the most reasonable way possible.   Support Mindscape on Patreon or Paypal. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Games play an important, and arguably increasing, role in human life. We play games on our computers and our phones, watch other people compete in games, and occasionally break out the cards or the Monopoly set. What is the origin of this human impulse, and what makes for a great game? Frank Lantz is both a working game designer and an academic who thinks about the nature of games and gaming. We discuss what games are, contrast the challenges of Go and Poker and other games, and investigate both the “dark energy” that games can sometimes induce and the ways they can help us become better people. Support Mindscape on Patreon or Paypal. Frank Lantz is a game designer and Director of the Game Center at New York University. He co-founded Area/Code games, and is the designer or co-designer of numerous popular games, including Drop7 and Universal Paperclips. He is also responsible for a number of large-scale real-world games. He has taught at New York University, Parsons School of Design, and the School of Visual Arts. Web site NYU web page Wikipedia Talk on Go, Poker, and the Sublime Talk on Logic and Emotions in Games Twitter Universal Paperclips QWOP See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Cosmologists have a standard set of puzzles they think about: the nature of dark matter and dark energy, whether there was a period of inflation, the evolution of structure, and so on. But there are also even deeper questions, having to do with why there is a universe at all, and why the early universe had low entropy, that most working cosmologists don’t address. Today’s guest, Anthony Aguirre, is an exception. We talk about these deep issues, and how tackling them might lead to a very different way of thinking about our universe. At the end there’s an entertaining detour into AI and existential risk. Anthony Aguirre received his Ph.D. in Astronomy from Harvard University. He is currently associate professor of physics at the University of California, Santa Cruz, where his research involves cosmology, inflation, and fundamental questions in physics. His new book, Cosmological Koans, is an exploration of the principles of contemporary cosmology illustrated with short stories in the style of Zen Buddhism. He is the co-founder of the Foundational Questions Institute, the Future of Life Institute, and the prediction platform Metaculus. Web site UCSC web page Google Scholar page Wikipedia Amazon.com author page Foundational Questions Institute Future of Life Institute Metaculus Twitter See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

It’s fun to spend time thinking about how other people should behave, but fortunately we also have an inner voice that keeps offering opinions about how we should behave ourselves: our conscience. Where did that come from? Today’s guest, Patricia Churchland, is a philosopher and neuroscientist, one of the founders of the subfield of “neurophilosophy.” We dig into the neuroscience of it all, especially how neurochemicals like oxytocin affect our attitudes and behaviors. But we also explore the philosophical ramifications of having a conscience, with an eye to understanding morality and ethics in a neurophilosophical context.   Support Mindscape on Patreon or Paypal. Patricia Churchland received her B.Phil. in philosophy from Oxford University. She is currently the President’s Professor of Philosophy (emerita) at the University of California, San Diego, as well as an adjunct professor of neuroscience at the Salk Institute. Among her awards are the MacArthur Prize, The Rossi Prize for Neuroscience and the Prose Prize for Science. Her latest book, Conscience: The Origins of Moral Intuition, was just released. She has arguably the best web site of any professional philosopher. Web site Google Scholar Amazon.com author page Wikipedia TEDx talk on The Brains Behind Morality Twitter See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

It’s easy to be cynical about humanity’s present state and future prospects. But we have made it this far, and in some ways we’re doing better than we used to be. Today’s guest, Nicholas Christakis, is an interdisciplinary researcher who studies human nature from a variety of perspectives, including biological, historical, and philosophical. His most recent book is Blueprint: The Evolutionary Origins of a Good Society, in which he tries to pinpoint the common features of all human societies, something he dubs the “social suite.” Marshaling evidence from genetics to network theory to accounts of shipwreck survivors, he argues that we are ultimately wired to get along, despite the missteps we make along the way.   Support Mindscape on Patreon or Paypal. Nicholas Christakis received an M.D. from Harvard Medical School and a Ph.D. in Sociology from the University of Pennsylvania. He is currently Sterling Professor of Social and Natural Science in the Department of Sociology, with additional appointments in the Departments of Ecology and Evolutionary Biology; Statistics and Data Science; Biomedical Engineering; Medicine; and in the School of Management. He is a member of the Institute of Medicine of the National Academy of Sciences and a Fellow of the American Association for the Advancement of Science. Yale web page Google scholar page Amazon.com author page Wikipedia Twitter See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.